Objective: to determine the survival rate of children with acute lymphoblastic leukemia treated in Hospital São Lucas -Pontifícia Universidade Católica -Rio Grande do Sul during the past 10 years. To evaluate well known prognostic factors and to compare results of BFM 90 and 95 trials.Methods: mixed cohort study of 0 to 15-years-old children treated with BFM 90 and 95 trials during the past 10 years at Hospital São Lucas -Pontifícia Universidade Católica -Rio Grande do Sul. Data were obtained from medical records. The occurrence of death was described by Kaplan-Meier survival curves. The overall effect of the prognostic factors was evaluated using the Cox's multivariate model.Results: sixty three patients, whose mean age (± standarddeviation) was 6.3 ± 4.2 years, were included. Thirty five patients (55.6%) were female. The estimated probability of relapse free survival at 5 years (± standard-error) was 50.8 ± 7.2% for all patients, with 77.7 ± 9.9% in the standard risk group, 41.3 ± 15.4% in the intermediate risk group, and 39.3 ± 13.7% in high risk group.Conclusions: the estimated probability of relapse free survival was below the results in developed countries. However the standard risk group obtained better prognostic but the small number of the cases doesn't allow permanent conclusions. Resultados: foram incluídos 63 pacientes, cuja média de idade (± desvio padrão) foi de 6,3 ± 4,2 anos. Trinta e cinco pacientes (55,6%) eram do gênero feminino. A probabilidade estimada de sobrevida livre de doença (± erro padrão) em 5 anos foi de 50,8 ± 7,2% para todos os pacientes estudados, sendo de 77,7 ± 9,9% para o risco básico, 41,3 ± 15,4% para o risco intermediário e 39,3 ± 13,7% para o alto risco.Conclusões: a probabilidade estimada de sobrevida situou-se abaixo dos resultados obtidos em países desenvolvidos. O grupo de crianças com risco básico, entretanto, obteve melhor prognóstico, mas o número restrito de casos não permite conclusões definitivas.