Mammary Analogue Secretory Carcinoma (Masc) of the Lower Lip in a Pediatric Patient

Haberland, Christel M.; Mukand-Cerro, Ian; Zhang, X.; Prasad, Mukesh; Wilk, A; Judson, Benjamin L.; Gnepp, Douglas R.

doi:10.1016/j.oooo.2017.06.071

Search citation statements

Order By: Relevance

Paper Sections

Select...

Discussion1

Citation Types

Supporting

Mentioning

Contrasting

Year Published

2021

Publication Types

Select...

Article1

Relationship

Self Cite0

Independent1

Authors

Journals

Cited by 1 publication

(1 citation statement)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…A literature review of pediatric salivary SC and MASC cases ( ≤ 18 y of age) yielded a total of 31 patients in addition to the 2 cases reported here (Table 1). 3,5,[13][14][15][16][17][18][19][20][21][22][23][24][25][26][27][28][29][30][31][32] Of these 33 pediatric cases, 18 were male and 15 were female. The median age at diagnosis was 14 years (range: 7 to 18 y).…”

Section: Discussionmentioning

confidence: 99%

Secretory Carcinoma of the Salivary Gland: A Rarity in Children

Kelly

Venkatramani

Quintanilla

et al. 2021

Journal of Pediatric Hematology/Oncology

View full text Add to dashboard Cite

Originally described as mammary analog secretory carcinoma (SC), SC of the salivary gland is a rare malignancy with morphologic and molecular similarities to SC of the breast. We present 2 children with salivary gland SC with the classic ETV6-NTRK3 gene fusion, including 1 with lymph node metastases. Both patients underwent surgical resection and were in remission 24 months postsurgery. One patient was additionally found to have synchronous papillary thyroid carcinoma with a TFG-MET fusion. A review of published cases highlights the expanding molecular profile and confirms the favorable course of salivary gland SC after surgical resection.

show abstract