Mamushi bites in a kidney transplant recipient

Abstract

Introduction Mamushi bites are the most common venomous snakebites in Japan. The clinical course of a common mamushi bite is known, and its alarming complication and cause of death are acute renal failure due to the venom. However, reports of mamushi bites in kidney transplant recipients are lacking, and the clinical course is unknown. Case presentation A 66‐year‐old man who was bitten by a mamushi 3 years after kidney transplantation. Similar to the course of a typical mamushi bite, his severity gradually worsened to its peak 3 days after the bite, after which he turned lightly. A sufficient amount of infusion and continued immunosuppressive drugs were used to avoid acute renal failure. Conclusion Even if the mamushi bite occurs in a kidney transplant recipient, the course and management may be the same as usual by continuing the immunosuppressive drugs and a sufficient amount of infusion.

Hyponatremia due to adrenal insufficiency after a Mamushi bite: a case report

“…In the second stage, microthrombosis due to disseminated intravascular coagulation (DIC), hypotension, and intracranial hypertension occurs, resulting in pituitary gland infarction and bleeding [ 10 ]. In general, the detailed components and physiological effects of snake venom are unknown, but because many components, such as phospholipase A2 and L-amino acid oxidase, are shared across species [ 2 , 11 ], Mamushi bites can cause the same pathological conditions as Russell’s viper bites.…”

“…Approximately 1000 cases of Mamushi bites are reported annually, with an estimated mortality rate of approximately 1% [ 1 ]. Known complications of Mamushi bites include acute kidney injury, hypovolemic shock, and rhabdomyolysis [ 2 ]. Although rare, fatal complications such as respiratory failure, gastrointestinal hemorrhage, and intestinal necrosis have also been reported [ 3 ].…”