In Colombia, a country with great climatic diversity, the water balance is affected in one way or another by climate change depending on the region. Thus, there may be increases and decreases in precipitation and, in all cases, a huge increase in temperature. This document presents some studies carried out in different areas of the country regarding the effects of climate change on water resources, including its influence on hydroelectric power generation, some changes in the water balance in arid areas, and the opportunity to ensemble climate change scenarios. Likewise, it outlines a possible future water supply-demand relationship, where supply is associated with a change in the water balance and demand with some crops, activities, and sectors that need water to survive. This allows to estimate some future status indices to see the overall picture of climate change in connection with the country's water resources.