Management and evolution of cervical intraepithelial neoplasia during pregnancy and postpartum

Cervical neoplasia in pregnancy. Part 1: screening and management of preinvasive disease

“…Such concerns have not been definitively confirmed, although they have been propagated in the literature. 19,31 Conversely, several studies have reported the liberal use of colposcopically directed biopsies in pregnancy. 27,[32][33][34] Although these studies were not designed to investigate the use of cervical biopsy in pregnancy specifically, they do not report significant bleeding complications or adverse pregnancy outcomes associated with the procedure.…”

“…In fact, CIN 1, 2, and 3 have all been associated with acceptably low rates of progression. Although Figure 3 demonstrates that it is possible for CIN 1 or CIN 2 to progress to CIN 3,30,31,35,67,69,71,72 this may represent a subpopulation of patients with less than optimal immunocompetence, or alternatively, sampling error during the antepartum biopsies. In either case, the significance of such a progression is of little concern.…”

Common Types of Cancer in Pregnancy

“…2 When a mass in the breast of a pregnant woman is noticed, it should be investigated. 14 Radiation therapy is contraindicated in pregnancy however some authors stated that radiotherapy is possible during pregnancy but, dependent on the fetal dose received, can result in poor fetal outcomes. 18,19 Radiotherapy and endocrine or antibody treatment should be postponed until after delivery according to some authors.…”

Nomenclatura Brasileira para Laudos Cervicais e Condutas Preconizadas: recomendações para profissionais de saúde

“…Estudos mostram que o risco de progressão de uma lesão de alto grau para carcinoma invasor durante o período gestacional é extremamente baixo e a regressão espontânea após o parto é relativamente freqüente (3,23,25,35) .…”