Management of a Hypomineralisation of the Enamel by Applying a Remineraliser Based on Zinc Hydroxyapatite (microRepair)

Abstract

According to our experience, the treatment with remineralising mousse based on biomimetic nanohydroxyapatite has the advantage of being easily implemented by all patients as it is economical and absolutely noninvasive. The following case report reports the results obtained from the use of a mousse based on biomimetic nanohydroxyapatite for the treatment of incisor and molar hypomineralisation. This case report illustrates the case of a 4-year-old patient who was diagnosed with MIH and was subjected to remineralising treatments at home for six months, at alternating periods. Throughout the observation period, the painful perception of the lesions was detected through an assessment scale, and the clinical appearance was documented photographically. One year after the diagnosis, all the elements involved no longer showed any symptoms.

Biomimetic hydroxyapatite paste for molar–incisor hypomineralization: A randomized clinical trial

“…(Bakkal et al, 2017;Biondi et al, 2017;Restrepo et al, 2016). This approach is based on the concept that increasing the mineral component in teeth affected by MIH can lead to an improvement of the physical structure of the enamel together with its aesthetic appearance, and to the decrease of dental sensitivity (Solinas et al, 2021).…”

“…Molar–incisor hypomineralization (MIH) is a delimited qualitative developmental defect leading to several dental complications, like hypersensitive teeth, increased susceptibility to caries, impaired chewing due to rapid tooth loss, and aesthetic defects; this condition may significantly affect patients' quality of life, so a correct diagnosis and treatment plan are strictly required (Solinas et al, 2021). To date, different clinical trials have been conducted to evaluate the efficacy of remineralizing agents like fluoride in different formulations, casein‐based mousses and amorphous calcium phosphate (CPP‐ACP), and hydroxyapatite (Bakkal et al, 2017; Biondi et al, 2017; Restrepo et al, 2016).…”

“…In this study, the primary outcome was pain sensation in response to tactile stimulus (Wong-Baker FACES Pain Rating Scale) 56 days after randomization.The results of the trial did not show the non-inferiority in hypersensitivity relief of the toothpaste containing hydroxyapatite compared to amine fluoride; however, the hydroxyapatite group tended to be less hypersensitive. In a pediatric sample, it was demonstrated that worse oral health quality of life is associated with MIH as regard oral symptoms(Portella et al, 2019) Therefore, a reduction in hypersensitivity with domiciliary treatment could surely bring to an improvement in MIH children's quality of life, as it is one of the major concerns during both daily life and dental treatment(Mendonça et al, 2022).In their recent case report,Solinas et al (2021) described the case of a 4-years-old female patient complaining of hypersensitivity to heat and cold, even during normal breathing. The patient presented hypomineralization of the enamel on permanent upper and lower incisors and left lower first permanent molar.…”

Patient Satisfaction with Resin Infiltration Treatment for Masking Noncavitated White Spot Lesions on Anterior Maxillary Teeth: Two Case Reports

“…A recent study by Solinas et al [17] reported that the application of biomimetic nanohydroxyapatite for the treatment of incisor and molar hypomineralization for six months in a 4-year-old patient resulted in a significant decrease in the hypersensitivity and improved the enamel appearance for the maxillary incisors. Further studies to evaluate the effect of biomimetic nanohydroxyapatite are recommended in hope that more invasive treatment options can be avoided.…”

“…Conservative methods for remineralization usually include proper oral hygiene measures, which requires patient's compliance and involves multiple applications of fluorides, and/or casein phosphopeptide-amorphous calcium phosphate containing products [14,15]. Recently, a few studies reported that the use of biomimetic hydroxyapatite containing toothpaste forms a coating on the enamel surface, promotes superficial enamel repair, and aids in preventing secondary caries around restorations [16,17,18].…”