Management of a Laryngeal Venous Malformation With Nd:YAG Laser and Bleomycin Sclerotherapy

Manna, Sayan; Meyer, A.; Shigematsu, Tomoyoshi; Berenstein, Alejandro; Courey, Mark S.

doi:10.1002/lary.28392

Cited by 4 publications

(4 citation statements)

References 18 publications

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“…Our case adds to the evidence for even large LVMs in adult populations being treated with sclerotherapy. Final removal of the lesion has been previously performed with neodymium-doped yttrium aluminium garnet laser;1 however, our case demonstrates that ultrasonic excision is also safe and effective.…”

Section: Discussionmentioning

confidence: 67%

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Successful use of sclerotherapy in giant supraglottic vascular malformation

Tsang,

Meghji,

Masterson

et al. 2024

BMJ Case Rep

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A young male patient presented with an incidental finding of a large supraglottic vascular lesion. The lesion was initially noted during intubation 4 years ago. Although originally listed for elective excision, there was a significant delay and at the time of surgery, the lesion proved too large to remove and a significant threat to the patient’s airway. An emergency tracheostomy was performed, followed by two consecutive treatments with sclerotherapy agents to reduce the size of the lesion. It was then successfully excised using a Thunderbeat ultrasound and bipolar dissection and cautery device.

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Section: Discussionmentioning

confidence: 67%

“…Laryngeal vascular malformations (LVMs) are rare, and the literature is limited to small case series and reports. They are however usually symptomatic, and patients can present with exertional fatigue, hoarseness or bleeding 1 2. The LVMs reported in the literature vary in terms of size and aetiology.…”

Section: Discussionmentioning

confidence: 99%

Successful use of sclerotherapy in giant supraglottic vascular malformation

Tsang,

Meghji,

Masterson

et al. 2024

BMJ Case Rep

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“…Sclerotherapy can be used as a single treatment method, or combined with flap surgery, laser, and other methods (17,18).…”

Section: Discussionmentioning

confidence: 99%

Clinical evaluation and animal experimental study of different mass concentrations of pingyangmycin in the local injection treatment of lip venous malformation

Yuan¹,

Wang²,

Xue³

et al. 2021

Ann Transl Med

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Background: This study investigated the clinical efficacy of different mass concentrations of pingyangmycin in the local injection treatment of lip venous malformation. An animal experimental study of the histopathological effects of different mass concentrations of pingyangmycin on the normal lip tissue of rabbits was also conducted. Methods: (I) We retrospectively analysed 98 out-patients with lip venous malformation in the Stomatological Hospital and the Fourth Affiliated Hospital of China Medical University from January 2008 to June 2013. The 98 cases were treated by local injection of different mass concentrations (8 mg/3 mL and 8 mg/5 mL) of pingyangmycin for the different sites of the lips. The clinical efficacy was observed, andadverse reactions were recorded. (II) 60 healthy male rabbits were randomly divided into three groups: a 8 mg/5 mL pingyangmycin group, a 8 mg/3 mL pingyangmycin group, and a control group. The right upper lips of the experimental groups were injected with 1ml pingyangmycin (8 mg/5 mL) and 1ml pingyangmycin (8 mg/3 mL) respectively, and the control group was injected with the same volume of normal saline. The thickness of the right upper lip of rabbits in the experimental groups and the control group was measured on the 21st, 28th, 35th, and 60th days after the first injection. Histopathological changes at the injection site were observed by light microscope and transmission electron microscope.Results: Venous malformations involving the skin tissues of the lips (pingyangmycin 8 mg/3 mL) had an effective rate of 93.62%, and those involving the labial mucosa tissues (pingyangmycin 8 mg/5 mL) had an effective rate of 98.04 %. In the animal experiment, there were statistically significant differences in the thickness of the injection site among the 8 mg/3 mL group, 8 mg/5 mL group, and the control group at different time points (P<0.01). Conclusions:The local injection of pingyangmycin in the treatment of lip venous malformations was efficient, safe and reliable. In the process of clinical application, attention should be paid when the concentration is 8 mg/3 mL to avoid local tissue atrophy and other complications.

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“…Sclerotherapy is the most commonly reported method for treating LVL. Sclerotherapy causes an obliteration of dysmorphic vessels endothelial cells, resulting in the devascularization of the vascular lesions 13 . Its main advantages are simple procedure and low risk of trauma.…”

Section: Discussionmentioning

confidence: 99%

Clinical Effects of Radiofrequency Coblation for Adult Laryngopharyngeal Vascular Lesions

2020

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Objective To explore the feasibility and efficacy of transoral radiofrequency coblation surgery (TRS) in the treatment of adult laryngopharyngeal vascular lesion (LVL). Methods A total of 15 patients with LVL were retrospectively studied, including 11 capillary lesions and five cavernous lesions (there was one case with two separate lesions). All of the lesions were treated with TRS alone (capillary lesion) or with a combination of TRS and sclerotherapy (cavernous lesion). The treatment efficacy was evaluated according to the modified Achauer criteria: grade 1, no change in size; grade 2, a decrease of < 50% in size; grade 3, a decrease of ≥ 50% but < 100%; and grade 4, the disappearance of the lesion with no recurrence for at least 6 months. Results The surgical procedures were successfully completed in all patients. According to the modified Achauer criteria, the treatment outcomes were grade 4 for 10 capillary lesions and one cavernous lesion; grade 3 for one capillary lesion and one cavernous lesion; grade 2 for one cavernous lesion; and grade 1 for two cavernous lesions, respectively. No complications related to the surgery, including bleeding, dysphagia, and infections, occurred after treatment. Conclusion The TRS is an effective treatment option for LVL, especially for patients with laryngopharyngeal capillary lesions. Level of Evidence 4 Laryngoscope, 131:566–570, 2021

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Management of a Laryngeal Venous Malformation With Nd:YAG Laser and Bleomycin Sclerotherapy

Cited by 4 publications

References 18 publications

Successful use of sclerotherapy in giant supraglottic vascular malformation

Successful use of sclerotherapy in giant supraglottic vascular malformation

Clinical evaluation and animal experimental study of different mass concentrations of pingyangmycin in the local injection treatment of lip venous malformation

Clinical Effects of Radiofrequency Coblation for Adult Laryngopharyngeal Vascular Lesions

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