2014
DOI: 10.1111/jdv.12434
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Management of actinic keratosis: a practical report and treatment algorithm from AKTeamTM expert clinicians

Abstract: This up-to-date expert opinions about AK and its treatment provide a management strategy and practical treatment algorithm for AK for French dermatologists to use.

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Cited by 101 publications
(128 citation statements)
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References 59 publications
(103 reference statements)
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“…Accurate detection and categorization of AK is relevant for the choice of lesion‐directed and field‐directed treatment; therefore, there is an increasing interest in non‐invasive imaging technologies in this field. However, three major problems still remain unresolved: first, how to distinguish unequivocally SCC from AK in a non‐invasive way; second, how to detect subclinical lesions in the context of field cancerization; and third, how to improve the diagnostic performance of these techniques when used by non‐expert physicians.…”
Section: Discussionmentioning
confidence: 99%
“…Accurate detection and categorization of AK is relevant for the choice of lesion‐directed and field‐directed treatment; therefore, there is an increasing interest in non‐invasive imaging technologies in this field. However, three major problems still remain unresolved: first, how to distinguish unequivocally SCC from AK in a non‐invasive way; second, how to detect subclinical lesions in the context of field cancerization; and third, how to improve the diagnostic performance of these techniques when used by non‐expert physicians.…”
Section: Discussionmentioning
confidence: 99%
“…However, they were conducted in patients both with isolated or multiple AKs, and we should be cautious in comparing these findings because, unlike MAL-PDT, cryotherapy is a lesion-directed treatment that is not considered one of the most suitable treatment options for patients with multiple superficial lesions [1,2,3,17]. In the first of these studies [13], a single MAL-PDT session was delivered, as in the present trial, and the complete remission rate of lesions was similar (68.7%).…”
Section: Discussionmentioning
confidence: 99%
“…Aunque existen muchos documentos de consenso y guías de manejo de las queratosis actínicas basados en reuniones de expertos, el grado de recomendació n de estas guías es bajo por definició n, y deben tomarse má s como documentos de formació n e informació n. Lo que está claro es que no existe un algoritmo consensuado y definitivo respecto al tratamiento de las queratosis actínicas, y ante la ausencia de ensayos clínicos comparativos entre sí de la mayoría de tratamientos disponibles 14 la elecció n debe basarse en la eficacia a corto plazo, y sobre todo a largo plazo, evidenciada en los ensayos clínicos aleatorizados y controlados con placebo usados para su aprobació n. Así pues, ademá s de la eficacia, efectos adversos, resultados esté ticos y mecanismo de acció n de un determinado tratamiento, su elecció n debe basarse en el tipo de queratosis actínicas, su nú mero, su extensió n, su localizació n, las características del paciente, su estado de salud, los antecedentes de transformació n a carcinoma epidermoide de queratosis actínicas previas y su capacidad para tener una buena adherencia, ademá s de la disponibilidad de un determinado tipo de tratamiento y el coste asociado al mismo [15][16][17][18][19][20] , sin olvidar en ningú n momento la experiencia y preferencias del dermató logo y del paciente previamente informado.…”
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