Management of cystic pancreatic lesions found incidentally

Barthet, Marc; Napoléon, Bertrand; Palazzo, Laurent; Chemali, M.; Létard, Jean-Christophe; Laugier, R.; Arpurt, Jean‐Pierre; Boyer, J.; Boustière, C.; Canard, J. M.; Cassigneul, J; Dalbiès, P. -A.; Escourrou, J.; Gay, G.; Ponchon, Thierry; Richard-Molard, B.; Sautereau, Denis; Tucat, Gilbert; Vedrenne, B.

doi:10.1055/s-2007-966786

Cited by 8 publications

(4 citation statements)

References 8 publications

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“…The diagnosis of SCN at EUS was based on the presence of a myriad of microcysts (2 mm or less) separated by thin septa, which sometimes appear as ‘layered’ and a thin cyst outline wall 18 19. In the absence of microcystic appearance, a low carcinoembryonic antigen (CEA) level in the cystic fluid was considered specific of SCN 20.…”

Section: Methodsmentioning

confidence: 99%

Serous cystic neoplasm of the pancreas: a multinational study of 2622 patients under the auspices of the International Association of Pancreatology and European Pancreatic Club (European Study Group on Cystic Tumors of the Pancreas)

Jaïs

Rebours

Malleo

et al. 2015

Gut

293

249

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Section: Methodsmentioning

confidence: 99%

Serous cystic neoplasm of the pancreas: a multinational study of 2622 patients under the auspices of the International Association of Pancreatology and European Pancreatic Club (European Study Group on Cystic Tumors of the Pancreas)

Jaïs

Rebours

Malleo

et al. 2015

Gut

293

249

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“…Patient demographic and clinical information was collected from the hospital medical record system. Demographic information (age and sex) and eight imaging factors known to be valuable in distinguishing SCNs from MCNs from previous studies were selected as the basis for constructing the clinical model (22,23). Two radiologists with considerable experience in abdominal imaging (13 and 6 years, respectively) evaluated the features in consensus including: (1) lesion size, (2) tumor location (head, neck, body, and tail), (3) cyst number (single or multiple), (4) calcification (absent or present), (5) septation (absent or present), (6) lesion shape (oval or irregular lobulation), (7) wall enhancement (absent or present), and (8) mural nodules (absent or present).…”

Section: Patient Populationmentioning

confidence: 99%

Multi-Phase CT-Based Radiomics Nomogram for Discrimination Between Pancreatic Serous Cystic Neoplasm From Mucinous Cystic Neoplasm

et al. 2021

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PurposeThis study aimed to develop and verify a multi-phase (MP) computed tomography (CT)-based radiomics nomogram to differentiate pancreatic serous cystic neoplasms (SCNs) from mucinous cystic neoplasms (MCNs), and to compare the diagnostic efficacy of radiomics models for different phases of CT scans.Materials and MethodsA total of 170 patients who underwent surgical resection between January 2011 and December 2018, with pathologically confirmed pancreatic cystic neoplasms (SCN=115, MCN=55) were included in this single-center retrospective study. Radiomics features were extracted from plain scan (PS), arterial phase (AP), and venous phase (VP) CT scans. Algorithms were performed to identify the optimal features to build a radiomics signature (Radscore) for each phase. All features from these three phases were analyzed to develop the MP-Radscore. A combined model comprised the MP-Radscore and imaging features from which a nomogram was developed. The accuracy of the nomogram was evaluated using receiver operating characteristic (ROC) curves, calibration tests, and decision curve analysis.ResultsFor each scan phase, 1218 features were extracted, and the optimal ones were selected to construct the PS-Radscore (11 features), AP-Radscore (11 features), and VP-Radscore (12 features). The MP-Radscore (14 features) achieved better performance based on ROC curve analysis than any single phase did [area under the curve (AUC), training cohort: MP-Radscore 0.89, PS-Radscore 0.78, AP-Radscore 0.83, VP-Radscore 0.85; validation cohort: MP-Radscore 0.88, PS-Radscore 0.77, AP-Radscore 0.83, VP-Radscore 0.84]. The combination nomogram performance was excellent, surpassing those of all other nomograms in both the training cohort (AUC, 0.91) and validation cohort (AUC, 0.90). The nomogram also performed well in the calibration and decision curve analyses.ConclusionsRadiomics for arterial and venous single-phase models outperformed the plain scan model. The combination nomogram that incorporated the MP-Radscore, tumor location, and cystic number had the best discriminatory performance and showed excellent accuracy for differentiating SCN from MCN.

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“…It has been reported to be from 1% to 4%. 19 In our case, if EUS guided CFA was carried out before the surgery and CEA level was checked, the operation might have been avoided. We only examined the intraoperative cystic amylase level, so it was impossible to exclude other cystic diseases.…”

Section: Discussionmentioning

confidence: 83%

A Case of Pancreatic Pseudocyst with an Atypical Multilocular Appearance on Endoscopic Ultrasound

Park¹,

Jung²,

Cho³

et al. 2010

Gut Liver

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Pancreatic pseudocysts are focal fluid collections that develop as a result of inflammatory diseases of the pancreas. They are managed conservatively or with a drainage procedure. Their radiological appearance can mimic cystic neoplasms of the pancreas. Pancreatic cystic neoplasms include various neoplasms with a wide range of malignant potential. Here, we report a patient with a pancreatic pseudocyst that presented with macrocystic attributes on endoscopic ultrasound.

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Management of cystic pancreatic lesions found incidentally

Cited by 8 publications

References 8 publications

Serous cystic neoplasm of the pancreas: a multinational study of 2622 patients under the auspices of the International Association of Pancreatology and European Pancreatic Club (European Study Group on Cystic Tumors of the Pancreas)

Serous cystic neoplasm of the pancreas: a multinational study of 2622 patients under the auspices of the International Association of Pancreatology and European Pancreatic Club (European Study Group on Cystic Tumors of the Pancreas)

Multi-Phase CT-Based Radiomics Nomogram for Discrimination Between Pancreatic Serous Cystic Neoplasm From Mucinous Cystic Neoplasm

A Case of Pancreatic Pseudocyst with an Atypical Multilocular Appearance on Endoscopic Ultrasound

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