Management of Gestational Diabetes Mellitus

Oskovi-Kaplan, Z. Aslı; Özgü-Erdinç, A. Seval

doi:10.1007/5584_2020_552

Cited by 29 publications

(24 citation statements)

References 72 publications

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“…Durante a gestação, existem também diversas alterações sistêmicas que podem prejudicar os desfechos perinatais, dentre elas, podem ser citadas: a anemia, o excesso de peso materno, o ganho ponderal excessivo na gravidez, o diabetes mellitus e a hipertensão arterial [5][6][7]18,19 .…”

Section: Resultsunclassified

Abordagem holística durante a gestação: alterações sistêmicas e suas repercussões na saúde bucal

Foratori‐Junior

Pereira

2021

Arch Health Invest

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Diversas alterações fisiológicas, imunológicas e hormonais ocorrem durante a gestação e quando associadas aos comprometimentos sistêmicos materno podem ter efeito sinérgico na saúde bucal das gestantes. O objetivo deste trabalho foi sintetizar as evidências científicas atuais de maior qualidade acerca da associação entre alterações sistêmicas e saúde bucal durante a gravidez. No período de agosto/2020 a março/2021, as seguintes bases de dados foram acessadas: EMBASE, SCOPUS, MEDLINE (Entrez PubMed), Web of Science, BVS/LILACS, e SCIELO. Foram incluídos estudos publicados entre janeiro/2000 a março/2021 em espanhol, inglês e/ou português. Devido às alterações imunológicas e hormonais da gravidez, a gengivite e a periodontite são as doenças bucais de maior prevalência nesse período. As alterações sistêmicas durante a gestação que comumente se associam à prejuízos na cavidade bucal são: anemia, sobrepeso/obesidade, ganho ponderal gestacional excessivo, diabetes mellitus e hipertensão arterial. Ademais, os acometimentos sistêmicos e periodontais na gestação podem prejudicar a saúde dos recém-nascidos. Entretanto, a obesidade e periodontite, apesar de estarem associadas, podem apresentar efeitos antagônicos na saúde dos recém-nascidos, visto que a obesidade se associa a macrossomia e a periodontite materna se associa à prematuridade e ao baixo peso ao nascer. Diante do exposto, conclui-se que diversas alterações sistêmicas se associam à piores parâmetros de saúde bucal durante a gravidez e esses fatores, conjuntamente ou isolados, podem resultar em efeitos perinatais adversos, afetando a saúde das mães e dos bebês.

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Section: Resultsunclassified

Abordagem holística durante a gestação: alterações sistêmicas e suas repercussões na saúde bucal

Foratori‐Junior

Pereira

2021

Arch Health Invest

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“…Gestational diabetes mellitus results from a reduction in pancreatic β-cell function, consequently, there is a reduction in carbohydrate metabolism, requiring an increase in insulin levels [12] . There is a triangular relationship between overweight/obesity, gestational diabetes mellitus and periodontitis.…”

Section: Discussionmentioning

confidence: 99%

“…In addition, systemic changes during pregnancy are associated with anemia, maternal weight gain, pregnancy-induced diabetes and arterial hypertension [8] , [9] , [10] , [11] , [12] . These outcomes are more significant in pregnant women with pre-existing obesity.…”

Section: Introductionmentioning

confidence: 99%

Is overweight associated with periodontitis in pregnant women? Systematic review and meta-analysis

Foratori‐Junior

Pereira²,

Gasparoto³

et al. 2022

Japanese Dental Science Review

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“…As there are no globally accepted criteria, different boards and colleges suggest distinct tests and glucose thresholds for diagnosing GDM [ 3 , 10 – 12 ], hampering comparison between studies. Other studies have suggested that 15–30% of women diagnosed with GDM cannot control glycemic levels with lifestyle modifications only and will require pharmacological treatment [ 3 , 13 ].…”

Section: Discussionmentioning

confidence: 99%

WHO criteria for diabetes in pregnancy: a retrospective cohort

Zaccara

Paganoti

Mikami

et al. 2022

BMC Pregnancy Childbirth

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Background Recognizing that hyperglycemia in pregnancy can impact both individually a patient’s health and collectively the healthcare system and that different levels of hyperglycemia incur different consequences, we aimed to evaluate the differences and similarities between patients who met the diagnostic criteria for gestational diabetes mellitus (GDM) or diabetes in pregnancy (DIP) according to the World Health Organization diagnostic criteria based on the 75 g oral glucose tolerance test (OGTT). Methods This retrospective study included a cohort of 1064 women followed-up at the Gestational Diabetes Unit of Hospital das Clinicas da Faculdade de Medicina da Universidade de Sao Paulo (Sao Paulo, Brazil). Patients were classified into GDM and DIP groups, according to their OGTT results. Their electronic charts were reviewed to obtain clinical and laboratory data for all participants. Results Women in the DIP group had a higher pre-pregnancy body mass index (30.5 vs 28.1 kg/m2, odds ratio [OR] 1.07, 95% confidence interval [CI] 1.02–1.11), more frequently experienced GDM in a previous pregnancy (25% vs. 11%, OR 2.71, 95% CI 1.17–6.27), and were more likely to have chronic hypertension (43.1% vs. 23.5%, OR 2.46, 95% CI 1.47–4.11), a current twin pregnancy (10.8% vs. 2.9%, OR 4.04, 95% CI 1.70–9.61), or require insulin (46.1% vs. 14.3%, OR 5.14, 95% CI 3.06–8.65) than those in the GDM group. Patients in the DIP group also had a higher frequency of large-for-gestational-age infants (12.3% vs. 5.1%, OR 2.78, 95% CI 1.23–6.27) and abnormal postpartum OGTT (45.9% vs. 12.6%, OR 5.91, 95% CI 2.93–11.90) than those in the GDM group. Nevertheless, in more than half of the DIP patients, glucose levels returned to normal after birth. Conclusions Diabetes in pregnancy is associated with an increased risk of adverse perinatal outcomes but does not equate to a diagnosis of diabetes post-pregnancy. It is necessary to identify and monitor these women more closely during and after pregnancy. Keeping patients with hyperglycemia in pregnancy engaged in healthcare is essential for accurate diagnosis and prevention of complications related to abnormal glucose metabolism.

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Management of Gestational Diabetes Mellitus

Cited by 29 publications

References 72 publications

Abordagem holística durante a gestação: alterações sistêmicas e suas repercussões na saúde bucal

Abordagem holística durante a gestação: alterações sistêmicas e suas repercussões na saúde bucal

Is overweight associated with periodontitis in pregnant women? Systematic review and meta-analysis

WHO criteria for diabetes in pregnancy: a retrospective cohort

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