Management of Nasal Septum Chondrosarcoma Occurring in Elderly: A Case Report

Belgioia, Liliana; Vaccara, E.M.L.; Bacigalupo, Almalina; Corvò, Renzo

doi:10.7759/cureus.1497

Cited by 7 publications

(12 citation statements)

References 8 publications

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“…Head and neck chondrosarcomas comprise hardly 5 to 10% cases. 1,3,4 Sinonasal cancers comprise 3% of all head and neck cancers that usually present as advanced disease with involvement of sinuses and nasal cavity simultaneously. Isolated origin of primary chondrosarcoma from nasal septum is found to be an extremely rare condition.…”

Section: Discussionmentioning

confidence: 99%

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Chondrosarcoma of the Nasal Septum—A Rare Subsite: Case Report with Review of Literature

Gupta

Pandey

Dimri

et al. 2021

Indian J Med Paediatr Oncol

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Chondrosarcomas are the second most common primary malignant bone tumors. Head and neck chondrosarcomas constitute less than 10% of these tumors, rarely arising from the nasal septum. These are locally aggressive malignant tumors arising from the cartilaginous framework of the nasal septum. Rarity of the tumor coupled with nonspecific symptoms makes it a diagnostic dilemma. Diagnosis requires endoscopy, radiology, and final histopathology for confirmation. Treatment is mainly surgical, requiring complete surgical excision with clear margins. Radiation has a role in unresectable tumors or for tumors with positive margins after surgery. Survival depends on the grade of tumor that predicts the metastatic potential of the tumor. We present a rare case of chondrosarcoma arising from the nasal septum in a 29-year-old young female presenting with complaints of nasal obstruction. Computed tomography was suggestive of a calcified cartilaginous tumor arising from the nasal septum. Endoscopic excision was done and postoperative histopathology showed grade II chondrosarcoma with clear margins. No adjuvant treatment was given to our patient and 2 years post-excision patient is disease free.To conclude, chondrosarcoma of the nasal septum is a rare tumor, with nonspecific symptoms. Surgery with clear margins remains the treatment of choice. Prognosis depends on the extent of tumor at presentation, resection margins, and grade of tumor.

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Section: Discussionmentioning

confidence: 99%

“…Tumors with localized and isolated involvement of nasal septum are rare. [2][3][4] These tumors most commonly present in the middle age. 5 Etiopathogenesis remains unknown.…”

Section: Introductionmentioning

confidence: 99%

Chondrosarcoma of the Nasal Septum—A Rare Subsite: Case Report with Review of Literature

Gupta

Pandey

Dimri

et al. 2021

Indian J Med Paediatr Oncol

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“…Chondrosarcoma with tendency for multiple recurrences and progressive spread is considered to have poor prognosis [5]. Chondrosarcoma of nasal cavity is a rare entity, and approximately 63 cases of chondrosarcoma originating from the nasal septum have been reported in review of literature from 1927 to 2017 [6]. Hereby, we are reporting a case of chondrosarcoma of nasal cavity with extension up to skull base and involvement of paranasal sinuses.…”

Section: Introductionmentioning

confidence: 88%

Chondrosarcoma of Nasal Cavity: a Rare Entity

Sahu

Goyal

Bothra

et al. 2020

Indian J Surg Oncol

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Chondrosarcoma of nasal cavity is a rare entity, and only few case reports exist. Diagnosis is made on histopathological analysis. Differentiating chondrosarcoma from chondromas can be challenging. Surgical excision remains the treatment of choice. We report a case of a 73-year-old male who presented to us with complaints of bilateral nasal obstruction. Histopathology reported as moderately differentiating chondrosarcoma. Patient subsequently underwent excision of tumor by craniofacial resection with adjuvant radiotherapy. Patient is on regular follow-up and has shown no evidence of recurrence.

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“…Rarely, it can develop in the craniofacial bones, 1,2 accounting for 8% of all head and neck sarcomas and only 0.1% of all head and neck malignancies 3 . Occurence of chondrosarcoma in the nasal cavity is uncommon, with less than 200 cases reported in the literature dating from 1950 4‐6 . Sinonasal chondrosarcoma is usually diagnosed in the third and fourth decade of life, 7,8 with nasal obstruction and congestion as the most frequently documented initial symptoms 5,8‐10 .…”

Section: Introductionmentioning

confidence: 99%