“…Lipomyelomeningocele (LMM) is neural tube defects (NTD), the disease is due at 18 ~ 28 d, premature epithelial ectoderm from neural ectoderm, mesenchymal cells into developing neural tube, the formation of fat affect the spinal cord, the fat through the catheter into the subcutaneous tissue, the disease often occurs in women, more than 30% of patients can be characterized by abnormal skin,Such as mass, fur sinus, vascular malformation, etc., all suggest that the patient may have abnormal neural tube development such as LMM.It can also be manifested as nerve damage, such as tetheredcord syndrome (TCS), such as defecation and urination dysfunction, lower limb motor sensation disorder, sexual dysfunction, etc. [11].Without timely intervention after the diagnosis of LMM, 90% of patients will develop irreversible progressive nerve damage [12].In many studies, through the inference of the natural history of this disease, it was believed that: most patients' symptoms gradually aggravated with time, including lower limb movement disorder, muscle weakness, equinovarus and high arch, and the symptoms gradually aggravated, and at this time, surgery was the only effective way to treat the symptoms at present;However, postoperative dysfunction of urine and feces, especially bladder function, cannot be improved [13].Long-term follow-up observation is needed after LMM operation to monitor the occurrence of LMM.LMM can occur months to years after surgery, with an incidence of 5% ~ 50% [14], manifested by gradual aggravation of original symptoms or new symptoms, such as pain, incontinence, sexual dysfunction, and weakness of both legs.After the postoperative stability of the patient's symptoms, new neurological symptoms or aggravation of the original symptoms should be evaluated for the presence of LMM.MRI examination is an important evidence to determine the presence or absence of LMM. Based on the presence or absence of lower spinal cord, syringomyelia, etc., the patient must be combined with clinical symptoms to make a correct judgment.…”