Management of unfavorable outcome after mild traumatic brain injury: Review of physical and cognitive rehabilitation and of psychological care in post-concussive syndrome

Examining the interdisciplinary approach for treatment of persistent post-concussion symptoms in adults: a systematic review

“…Traditionally, RCTs are considered gold standard for research, however, this is being questioned for the heterogenous condition that is TBI or concussion. Research into rehabilitation, the context within which PPCS is commonly addressed, does not fit well with the use of RCTs either (Horn et al, 2015). The strict controls required result in evidence based on select subpopulations which then limits translation back to the general population (Menon & Maas, 2015).…”

“…Current research, such as the Silverberg and Iverson led expert panel working to update the definition of mTBI, will likely provide useful progress regarding clarifying necessary definitions (Silverberg et al, 2021). With evidence suggesting the way forward is multimodal intervention with capacity and flexibility for individualisation, new perspectives on determining evidence and the ability to replicate quality studies provides hope that some of the challenges inherent in TBI research can begin to be addressed (Horn et al, 2015;Jaganathan & Sullivan, 2019). This review provides a foundation for further research into persistent symptoms following concussion for adults.…”

“…The strict controls required result in evidence based on select subpopulations which then limits translation back to the general population (Menon & Maas, 2015). Systematic reviews of evidence within the TBI context have consistently resulted in determining a lack of high-quality research and evidence-based treatments or inability to analyse the significantly varied results (Arbabi et al, 2020; Heslot et al, 2021; Möller et al, 2021). Comparative effectiveness research (CER) has somewhat recently been suggested as an alternative.…”

Multi-modal intervention for neuropsychological symptoms following traumatic brain injury: A case report

“…[ 5 ] Various combinations of treatment modalities have been tried in the management of cognitive symptoms following mild TBI; however, the results are not encouraging. [ 6 ] Add on tRNS has been used in patients with prominent cognitive impairments associated with TBI and encephalitis, with improvement of cognitive functions. [ 7 ] Murphy et al .…”