Management residues of chlorpyrifos insecticides on shallot cropping through remediations technology

Poniman,; Indratin,; Ardiwinata, Asep Nugraha; Rianto, Sugeng

doi:10.1088/1755-1315/648/1/012072

Cited by 4 publications

(2 citation statements)

References 18 publications

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“…Chlorpyrifos is a broad-spectrum chlorinated insecticide that is easily absorbed from the intestines and lungs of humans and animals. [ 1 ] Chlorpyrifos is metabolized in the liver by the oxidation reaction of cytochrome P450 (CYP), which forms the toxic oxon metabolism of chlorpyrifos. [ 2 ] Chlorpyrifos-oxon inhibits acetylcholinesterase activity in target tissues, resulting in the accumulation of endogenous ACh, which causes overstimulation and disturbance of nervous system activity.…”

Section: Introductionmentioning

confidence: 99%

The effect of chlorpyrifos oral exposure on the histomorphometric and kidney function in Wistar rat

Sakinah,

Wisudanti,

Abrori

et al. 2024

Indian Journal of Pharmacology

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BACKGROUND: Chlorpyrifos belongs to a broad-spectrum organophosphate insecticide that has high toxicity, is metabolized in the liver by the oxidation reaction, and can inhibit acetylcholinesterase activity. Acetylcholinesterase inhibition generates the reactive oxygen species and induces oxidative stress, which ultimately results in cellular damage like in the kidney. Examining blood urea nitrogen (BUN) levels, creatinine, and kidney histopathology is an appropriate indicator to assess the toxicity of chlorpyrifos to the degree of damage to cells and kidney tissue. MATERIALS AND METHODS: This research used to determine the effect of duration of exposure to chlorpyrifos and dose–response relationships is important for early detection of the effects of chlorpyrifos toxicity on health. The research study was a true experimental (completely randomized design) consisting of 30 subjects divided into 5 groups. Controlled Group (K1) given 1 mg/kg BW Tween 20 and NaCl 0, 9% until the 56th day. The chlorpyrifos exposed group (P1, P2, P3, and P4) was given chlorpyrifos 5 mg/kg BW for 7, 14, 28, and 56 days. After the treatment, BUN and creatinine levels were measured, and microscopic changes in the kidney were analyzed. The results of BUN, creatinine, and kidney histopathologic were analyzed using the analysis of variance statistical test. RESULTS: The data result showed that compared to the control group, there were significant increases of BUN and creatinine (P = 0.013 and P = 0.003). Histopathological examinations of kidney glomerulus diameter were also smaller compared to the control group (P = 0.00). All the data measurement indicates significant differences compared to the control group. CONCLUSIONS: We concluded that sub-chronic oral exposure to chlorpyrifos at low doses can damage the kidneys and cause kidney failure.

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Section: Introductionmentioning

confidence: 99%

The effect of chlorpyrifos oral exposure on the histomorphometric and kidney function in Wistar rat

Sakinah,

Wisudanti,

Abrori

et al. 2024

Indian Journal of Pharmacology

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“…Pesticides have been used globally to control pests and diseases in cultivated plants [1][2][3][4]. More broadly, pesticides are also used in the health sector to eradicate disease vectors and other pests [5][6].…”

Section: Introductionmentioning

confidence: 99%

Distribution of chlorpyrifos residue in maize (Zea mays)

Zu’amah,

Harsanti,

Wihardjaka

et al. 2023

IOP Conf. Ser.: Earth Environ. Sci.

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Chlorpyrifos is an organophosphate insecticide. It has low aqueous solubility, is volatile and non-mobile, moderately persistent in soil, highly toxic to mammals, and is an acetylcholinesterase inhibitor. The main use of chlorpyrifos is to control various types of agricultural pests. This study aims to determine the absorption of chlorpyrifos residues in maize plants. The study was conducted in July-December 2019. Experimental research was conducted at Jakenan experimental field on land contaminated with chlorpyrifos residue. The maize used was a hybrid maize variety NK 6172 Perkasa. Pesticide residue analysis was carried out at the Laboratory of the Agricultural Environmental Research Institute (IAERI). The results showed that the highest chlorpyrifos residue was in the stalks and leaf with a value of 0.0318-0.5682 mg kg−1 but still below the maximum residue limit (MRL) of 10 mg kg−1 recommended by The National Standardization Agency of Indonesia. The concentration of chlorpyriphos residue in maize grain is 0.0014-0.2203 mg kg−1 (MRL=0.05 mg kg−1). Chlorpyriphos residue in the soil is 0.0148-0.0786 mg kg−1 (MRL=3.2 mg kg−1), and the lowest was root (<0.0014 mg kg−1). Information on residue distribution on maize and soils can be helpful as an early warning about the use of insecticides and food safety measures.

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Nano-biochar interactions with contaminants in the rhizosphere and their implications for plant-soil dynamics

Sarma,

Shyam,

Zhang

et al. 2024

Soil & Environmental Health

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Management residues of chlorpyrifos insecticides on shallot cropping through remediations technology

Cited by 4 publications

References 18 publications

The effect of chlorpyrifos oral exposure on the histomorphometric and kidney function in Wistar rat

The effect of chlorpyrifos oral exposure on the histomorphometric and kidney function in Wistar rat

Distribution of chlorpyrifos residue in maize (Zea mays)

Nano-biochar interactions with contaminants in the rhizosphere and their implications for plant-soil dynamics

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