BACKGROUNDA fistula-in-ano is an abnormal tract or cavity establishing a communication between rectum or anal canal and the perianal area. Surgery is the treatment of choice with the goals of draining infection, eradicating the fistulous tract and avoiding persistent or recurrent disease while preserving anal sphincter function. Various surgical options available include fistulotomy/fistulectomy with seton wire placement, advanced flaps, fistula plugs, fibrin glue and more recently newer techniques such as Ligation of the intersphincteric fistula tract (LIFT), Video-assisted anal fistula treatment (VAAFT) and FILAC technique (Fistula-Tract Laser Closure).The present study was conducted to assess and compare the outcome of LIFT procedure and Seton wire placement in complex fistula-in-ano.