Manchester and Oxford University Scale for the Psychopathological Assessment of Dementia

Abstract

There is increasing awareness of the importance of psychopathological and behavioral changes in dementia and a need for a technique to measure these noncognitive features. Such a schedule should keep screening questions to a minimum, include a severity measure, exclude symptoms resulting from physical illness, be as brief as possible, and not mix domains of psychopathology. To test the reliability, sensitivity, and validity of a newly developed test, 30 carers were interviewed four times during 6 weeks. An obligatory stem question in each category was followed by supplementary questions. The interviewer recorded the presence of each symptom, its severity, when each symptom started, its duration, and whether it was still present. To detect the presence of delusions, the informant was asked about the patient's insight. Satisfactory differences in mean Kvalues weredemonstrated in test-retest and interrater reliability and validity compared with other techniques. This test may be useful to measure the outcome of drug trials, for correlating psychopathological and behavioral changes with autopsy findings and in epidemiological surveys.

Sintomas psiquiátricos entre pacientes com demência atendidos em um serviço ambulatorial

“…Cabe, ainda, destacar que o instrumento utilizado para investigar a presença de morbidade psiquiátrica entre os nossos pacientes (SRQ-20) não foi, ainda, adequadamente validado para esse propósito. Escalas como o BEHAVE-AD 25 , 'Neuropsychiatric Inventory 26 ' e a 'Manchester and Oxford University Scale for the Psychopathological Assessment of Dementia 27 ' têm sido preferencialmente utilizadas com essa finalidade. No entanto, vale ressaltar que o SRQ-20 foi adequadamente validado para o rastreamento de morbidade psiquiátrica em nosso meio 11 , inclusive entre indivíduos idosos 12 .…”

Determinants of carer stress in Alzheimer's disease

“…Information obtained from carer responses to questions dealing with these issues in the CFI was used to complete the corresponding sections on the CSDD. Carers reported on the levels of behavioural disturbances and psychotic symptoms in patients using the Manchester and Oxford Scale for Psychopathological Assessment in Dementia (MOUSEPAD; Allen et al, 1996). This questionnaire has two sections: one which assesses psychotic phenomena (hallucinations, misidenti®cations, reduplications and delusions) and another which assesses behavioural disturbances (walking, eating, sleeping, sexual behaviour, aggression and emotional lability).…”

“…Thus, past research ®ndings should be interpreted as indicating that a set of symptoms most predominantly, but not exclusively, composed of NCFs show a fairly consistent relationship with carer stress. In light of this problem and the availability of several scales with good content validity for measuring NCFs (Allen et al, 1996), a re-examination of the relationship between these features and carer stress is both necessary and possible. 2.…”

Caring for a relative with dementia: family caregiver burden

“…Women seem to have lower levels of mastery (Rose-Rego et al 1998) and use less effective coping strategies (Thoits 1995), while men use mostly problem-solving approaches (Thomson et al 2004). Some authors explain sex differences by suggesting that men receive more informal support than women (Allen et al 1996, Ingersoll-Dayton et al 1996.…”

“…2004). Some authors explain sex differences by suggesting that men receive more informal support than women (Allen et al. 1996, Ingersoll‐Dayton et al.…”