Mania following organophosphate poisoning

Abstract

Organophosphate poisoning is the most common poisoning in developing countries. Although the acute muscarinic and nicotinic side-effects of organophosphate poisoning are well known and easily recognized, but neuropsychiatric changes are rarely reported. We are reporting a case of a 33-year-old female who developed manic episode following acute organophosphate poisoning.

Management of organophosphorus poisoning and the role of magnesium sulfate: A scoping review of literature

“…However, it is important to note that intentional poisoning incidents involving these readily accessible pesticides have also been reported. Organophosphate poisoning (OP), in general, accounts for approximately 50% of hospital admissions related to poisoning, particularly in developing countries [1,2].…”

Commentary

“…In the article, entitled “Mania following organophosphate poisoning”[ 1 ] the authors reported occurrence of a neuropsychiatric condition, mania in a 33-years old female followed by acute organophosphorus compound (OPC), chlorpyrifos (CPF) poisoning. A similar case report was presented by Bradwell 1964[ 2 ] in a farm exposure with demeton-S-methyl, an OPC.…”