Manipulation of micro-particles through optical interference patterns generated by integrated photonic devices

Hsu, Li-Chung; Chen, Te-Chang; Yang, Yao-Tsu; Huang, Chieh-Yang; Shen, Dawei; Chen, Ya-Tzu; Lee, Ming-Chang M.

doi:10.1039/c2lc41163f

Cited by 24 publications

(10 citation statements)

References 19 publications

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“…With low propagation losses and by combining confinement and divergence, rib waveguides are promising for integration in lab-on-a-chip systems [20][21][22] where particle trapping and manipulation is required. By tuning the waveguide geometry to the exact application, the performance can be optimized while requiring a single lithographic step.…”

Section: Discussionmentioning

confidence: 99%

Rib waveguides for trapping and transport of particles

2016

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Rib waveguides are investigated as an alternative to strip waveguides for planar trapping and transport of microparticles. Microparticles are successfully propelled along the surface of rib waveguides and trapped in the gap between opposing rib waveguides. The trapping capabilities of waveguide end facets formed by a single and opposing waveguide geometries are investigated. The slab beneath a rib waveguide continues to guide light after the end facet of a rib waveguide. Thus particles can be trapped in wider gaps formed by opposing rib waveguides than with strip waveguides. Rib waveguides were found more efficient in trapping a collection of particles in the gap and particles could be moved to different locations in the gap by changing the relative power in the two opposing rib waveguides. Numerical simulations are used to show that the trapping efficiency on the surface of rib and strip waveguides is comparable. The simulations also confirm the advantage of opposing rib waveguides for trapping particles in wide gaps. The low sidewalls of rib waveguides give low propagation losses and make it easy to integrate rib waveguides with other functions in a lab-on-a-chip where particle trapping and transport is required.

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Section: Discussionmentioning

confidence: 99%

Rib waveguides for trapping and transport of particles

2016

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“…Moreover, 1 × 2 splitters have also been implemented using multimode interference (MMI) waveguides [67, 68]. Here, the power ratio between the two output ports can be tuned by wavelength and various particle splitting ratios were observed [69, 70]. Another clever way to transfer power, and concomitantly microspheres, between waveguides is to place two waveguides in close proximity.…”

Section: Optofluidic Particle Manipulationmentioning

confidence: 99%

“…By the proper design of the coupling gap and coupling length, one can achieve different output power ratios. Optical manipulation and lateral transfer of 10 mm polystyrene spheres was achieved on such a waveguide-based directional coupler using the gradient force across the small gap at a certain interaction length [70]. Because the coupling length also depends on the input laser wavelength, the coupling transfer efficiency can again be controlled by tuning the input laser wavelength.…”

Section: Optofluidic Particle Manipulationmentioning

confidence: 99%

Optofluidic bioanalysis: fundamentals and applications

et al. 2017

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Over the past decade, optofluidics has established itself as a new and dynamic research field for exciting developments at the interface of photonics, microfluidics, and the life sciences. The strong desire for developing miniaturized bioanalytic devices and instruments, in particular, has led to novel and powerful approaches to integrating optical elements and biological fluids on the same chip-scale system. Here, we review the state-of-the-art in optofluidic research with emphasis on applications in bioanalysis and a focus on waveguide-based approaches that represent the most advanced level of integration between optics and fluidics. We discuss recent work in photonically reconfigurable devices and various application areas. We show how optofluidic approaches have been pushing the performance limits in bioanalysis, e.g. in terms of sensitivity and portability, satisfying many of the key requirements for point-of-care devices. This illustrates how the requirements for bianalysis instruments are increasingly being met by the symbiotic integration of novel photonic capabilities in a miniaturized system.

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“…Two main approaches have been investigated heretofore (8). The first one consists in using the light propagating in a waveguide to trap and propel particles as on a conveyor belt (4,5,(9)(10)(11)(12)(13)(14)(15)(16). However, this strategy usually fails whenever trapped particles' propulsion has to be stopped, requiring more complex and restrictive implementation based on irregular waveguide geometries (17), microfluidic channel walls (18), or counter-propagating modes (8,(19)(20)(21)(22)(23)(24).…”

Section: Introductionmentioning

confidence: 99%

Optical tweezing using tunable optical lattices along a few-mode silicon waveguide

Jager

Tardif

et al. 2018

Lab Chip

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Fourteen years ago, optical lattices and holographic tweezers were considered as a revolution, allowing for trapping and manipulating multiple particles at the same time using laser light. Since then, near-field optical forces have aroused tremendous interest as they enable efficient trapping of a wide range of objects, from living cells to atoms, in integrated devices. Yet, handling at will multiple objects using a guided light beam remains a challenging task for current on-chip optical trapping techniques. We demonstrate here on-chip optical trapping of dielectric microbeads and bacteria using one-dimensional optical lattices created by near-field mode beating along a few-mode silicon nanophotonic waveguide. This approach allows not only for trapping large numbers of particles in periodic trap arrays with various geometries, but also for manipulating them via diverse transport and repositioning techniques. Near-field mode-beating optical lattices may be readily implemented in lab-on-a-chip devices, addressing numerous scientific fields ranging from bio-analysis to nanoparticle processing.

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Manipulation of micro-particles through optical interference patterns generated by integrated photonic devices

Cited by 24 publications

References 19 publications

Rib waveguides for trapping and transport of particles

Rib waveguides for trapping and transport of particles

Optofluidic bioanalysis: fundamentals and applications

Optical tweezing using tunable optical lattices along a few-mode silicon waveguide

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