Manometry of canine ileocolonic sphincter: comparison of sleeve method to point sensors

Abstract

Tonic and phasic pressures at the canine ileocolonic sphincter (ICS) were recorded by a manometric assembly that combined a sleeve sensor with multiple side-hole pressure ports. By aligning the side holes precisely it was possible to evaluate in vivo the fidelity of the sleeve relative to simultaneous pressure records from the point sensors. The ICS exhibited tonic and phasic pressures, often in excess of 100 cmH2O of pressure. The sleeve sensor was tolerant of small, but potentially important, movements of the assembly relative to the ICS. Point sites of recording moved in and out of the high-pressure zone and side holes were, therefore, not ideal sensors of sphincteric tone. The anticipated properties of this sleeve, that it would display reduced fidelity for rapid changes in pressure at sites away from its point of perfusion, were confirmed in vivo. The sleeve also "summarized" phasic bursts and was unable to monitor propagation of such events. However, the combined assembly proved excellent for examining overall function of the canine ICS.

Functional evaluation of the ileocolic sphincter transplanted to the neck using microsurgery technique: a manometric study in dogs *

“…In the literature, ICS pressure values in dogs vary between 14 and 47 mmHg. 13 –15 Therefore, the values observed in the present research agree with the literature. These values did not change after transplantation.…”

“…The ICS lengths obtained in this work agreed with the range (1–3 cm) for small animals (e.g. dog) reported in the literature 13 –17…”

The ileocolonic sphincter

“…In addition, muscle strips from the ileocolonic junction show isometric tone of myogenic origin 2,3 . In conscious dog, using an elegant surgical preparation allowing an easy access to the ICS, a high‐pressure zone of 26 mmHg over a distance of about 3 cm is recorded during the pioneer studies of Quigley et al 4–6 . Later, a high‐pressure zone has been found in other mammals by various research teams.…”

Motor Activity of the Distal Ileum and Ileocecal Sphincter and Its Relation to the Region’s Function

“…Using an assembly which combined a per fused sleeve with multiple closely spaced side holes [37], unique, highly coordinated interdigestive motor patterns have recently been defined in the canine ileocolonic junc tional region [24]. While sustained tone was confined to the immediate vicinity of the ICS, unique phasic patterns were noted over a longer, functionally distinct, area which incorporated not only the ICS but also 30 cm of distal ileum and 5 cm of proximal colonthe ileocolonic junctional segment ( fig.…”