The main goal of this article is to appraise the existence of different patterns of the Entrepreneurial Ecosystems, to identify its relationship with Entrepreneurial Initiative, and recommend entrepreneurship policies that may influence the growth of entrepreneurial action. Without evidence on entrepreneurial ecosystems landscape and what determinants stimulate entrepreneurship in a given environment, policies could become flawed and miss the target. To address research purposes, the analysis was performed using data extracted from the Global Entrepreneurship Monitor (GEM) Database carried out between 2010 and 2016. To ensure a longitudinal perspective, it was used a balanced panel approach followed by Logistic Regression estimations. The article offers a novel and systematic approach, the Entrepreneurial Ecosystem Taxonomy, to overcome a disaggregated perspective on entrepreneurial ecosystems, between individual and context levels. Empirical findings capture four different country profiles, based on two measures: Entrepreneurial ecosystems and entrepreneurial initiative. The results allow to compare the four groups and appraise significant disparities around entrepreneurship determinants, namely, the education factor. While education is commonly recognized as a positive influence on entrepreneurship, the results suggest a contradictory effect. The existence of differentiated profiles and its determinants points outs the importance of developing specific entrepreneurship policy packages attending group specificities.