In recent years, the ecological and environmental problems of the Yellow River Basin have gradually become our concern, and sedimentation at the mouth of the Yellow River can directly demonstrate the treating effect of the Yellow River. However, the research and monitoring of the Yellow River environment based on GIS technology is not in-depth enough, and only a few studies have a very effective interpretation of the future changes in the estuary of the Yellow River. Therefore, this study explores the inter-annual variation of sediment sedimentation in the estuary of the Yellow River by collecting Landsat satellite data and using QGIS software for data analysis, feature classification and inter-annual change. The linear fitting model of MATLAB software shows that the total sediment sedimentary area of the mouth of the Yellow River showed a downward trend in the decade from 2013 to 2022, which is closely related to natural factors such as ocean currents and waves and fortifications built by man. Therefore, the environment of the Yellow River has changed well in the past decade, and the governance will continue to strengthen on this basis.