Marcus-Gunn Jaw Winking Syndrome and Gustatory Sweating in Long Standing Poorly Controlled Diabetes: A Case Report

Dutta, Deep; Maisnam, Indira; Ghosh, Sujoy; Mukhopadhyay, Pradip; Mukhopadhyay, Satinath; Chowdhury, Subhankar

doi:10.4236/ijcm.2012.31008

Cited by 4 publications

(4 citation statements)

References 8 publications

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“…In another case, a 44‐year‐old man with 24 years of T1DM and a recent onset of GS showed an increase in HbA1c from 60 to 72 mmol/mol 6 . Some case reports of patients with T2DM and GS also report high HbA1c as associated with GS 15,16 . Poor glycaemic control may impact the risk for GS, and the potential mechanism should be addressed in further studies.…”

Section: Discussionmentioning

confidence: 96%

“…Even though GS caused by Frey's syndrome or surgical complications has been mentioned as early as 1757, 12 , 13 , 14 the first cases of GS in diabetes were published by Watkins et al 5 in 1973. Since then, the phenomenon has mainly been described in case reports 4 , 7 , 15 , 16 , 17 , 18 , 19 , 20 , 21 and has been referred to as a common symptom of diabetic autonomic neuropathy in a study by Shaw et al 10 …”

Section: Discussionmentioning

confidence: 99%

“… 6 Some case reports of patients with T2DM and GS also report high HbA1c as associated with GS. 15 , 16 Poor glycaemic control may impact the risk for GS, and the potential mechanism should be addressed in further studies.…”

Section: Discussionmentioning

confidence: 99%

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Gustatory sweating in people with type 1 and type 2 diabetes mellitus: Prevalence and risk factors

Klarskov

Rohden

Thorsteinsson

et al. 2021

Endocrino Diabet & Metabol

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Objective Gustatory sweating (GS) is characterized by profuse sweating during or immediately after ingestion of food and is known as a complication of diabetes mellitus (DM). This study aimed to determine the prevalence of GS and to characterize the sweating in a cohort of patients with type 1 and type 2 diabetes mellitus (T1DM and T2DM) as compared with a control group. Methods In a cross‐sectional study, 665 outpatients with T1DM and 505 outpatients with T2DM filled in an 8‐point questionnaire about GS. Answers were paired with medical data from the electronic patient records to explore associations with DM complications. The control group consisted of 1158 persons without DM answering the same questionnaire in an online version. Results In people with T1DM and T2DM, the prevalence of GS was 10% (95% CI 7%–12%) and 13% (95% CI 10%–16%), respectively. In the control group, the prevalence of GS was 5% (95% CI 3%–6%). Most commonly, people sweat on the face and/or head and upper body with a duration of 10–30 min albeit in the control group <10 min. In patients with T1DM, increased HbA1c was associated with GS (OR 1.3 [95% CI 1.05–1.6], p = .016), and in T2DM, younger age (OR 0.95 [95% CI 0.92–0.99), p = .006), presence of severe peripheral neuropathy (OR 2.33 [95% CI 1.04–5.2], p = .039) and absence of proliferative retinopathy were associated with GS (OR 0.22 [95% CI 0.07–0.71], p = .011). Conclusion We found the prevalence of gustatory sweating of 11% in a hospital‐based cohort of patients with T1DM and T2DM. This was twice as high as in non‐diabetic control persons. Associations between GS and known diabetes complications could only be demonstrated in T2DM. Compared with a control group without DM, odds for GS are higher in people with DM and age >45.

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Section: Discussionmentioning

confidence: 96%

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Gustatory sweating in people with type 1 and type 2 diabetes mellitus: Prevalence and risk factors

Klarskov

Rohden

Thorsteinsson

et al. 2021

Endocrino Diabet & Metabol

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“…However, MGJWP with ptosis has been reported to be associated with DRS in Mobius sequence, pseudo- inferior oblique over action (Y pattern exotropia due to lateral rectus activation on upgaze), trigemino-abducens synkinesis and gustatory sweating in poorly controlled diabetes. [ 20 21 22 23 ] In our case series, we didn't submit the patients to a pediatric neurologist's opinion. However, it would be a good practice to rule out other systemic manifestations.…”

Section: Discussionmentioning

confidence: 99%

The rare phenomenon of Marcus-Gunn jaw winking without ptosis: Report of 14 cases and review of the literature

Alam

Nishanth

Ramasubramanian

et al. 2020

Indian J Ophthalmol

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Purpose: To report a rare case series of 14 patients of the Marcus-Gunn jaw-winking phenomenon (MGJWP) without ptosis. Methods: This was a retrospective noninterventional case series. The medical records of all patients diagnosed with MGJWP over the past 10 years were retrieved. Patients with documented evidence of absence of ptosis were segregated and analyzed for visual acuity, the severity of Marcus-Gunn, the presence of squint and amblyopia, and the presence of other aberrant regenerations. Results: A total of 207 patients were diagnosed with MGJWP, out of which 14 (6.76%) patients had isolated MGJWP without blepharoptosis. The mean age of presentation was 9.5 years and males and females were equally affected. The left eye was involved more commonly (57.2%) than the right eye. Twelve patients were congenital and two were presumed to be of traumatic origin. The most common refractive error in this cohort was astigmatism (10, 71.42%), followed by hyperopia (5, 35.71%). One patient had anisometropic amblyopia. Marcus-Gunn was found to be mild (≤2 mm of lid excursion) in all cases. None of the patients had strabismus or any other aberrant innervations. None of the patients underwent surgery and did not develop ptosis or worsening or improvement of Marcus-Gunn after a mean follow-up period of 2.3 years. Conclusion: Isolated MGJWP in the absence of ptosis is a very rare entity and this is the largest series to date to report such an occurrence. All patients had a mild form of MGJWP with no intervention required in any of the cases.

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Trigemino-oculomotor synkinesis: Report of a rare case

Joshi

Tailor

Ghugare

2014

J Indian Acad Oral Med Radiol

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Marcus-Gunn Jaw Winking Syndrome and Gustatory Sweating in Long Standing Poorly Controlled Diabetes: A Case Report

Cited by 4 publications

References 8 publications

Gustatory sweating in people with type 1 and type 2 diabetes mellitus: Prevalence and risk factors

Gustatory sweating in people with type 1 and type 2 diabetes mellitus: Prevalence and risk factors

The rare phenomenon of Marcus-Gunn jaw winking without ptosis: Report of 14 cases and review of the literature

Trigemino-oculomotor synkinesis: Report of a rare case

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