Marine Biotechnology for Production of Food Ingredients

Rasmussen, Rosalee S.; Morrissey, Michael T.

doi:10.1016/s1043-4526(06)52005-4

Cited by 252 publications

(148 citation statements)

References 110 publications

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“…Till date, they have been reported as potent pharmacological and medicinal agent having hepato-protective (Vadiraja et al 1998), anti-inflammatory (Romay et al 2003), anti-cancerous , anti-Alzheimer's disease , and antioxidant activity (Sonani et al 2014;Soni et al 2008). Moreover, PBPs are also utilized as natural colorants in food products like chewing gums, dairy products, jellies as well as in cosmetics (Rasmussen and Morrissey 2007). Phycoerythrin (PE), a majorly produced PBP, is an oligomeric pigment protein, consisting of two chromophore/s-appended dissimilar polypeptide chain belonging to two different families (α and β) (Parmar et al 2011).…”

Section: Introductionmentioning

confidence: 99%

Phycoerythrin extends life span and health span of Caenorhabditis elegans

Sonani

Singh²,

Awasthi

et al. 2014

AGE

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In the present study, we tested the antioxidant activity of phycoerythrin (PE, an oligomeric light harvesting protein isolated from Lyngbya sp. A09DM) to curtail aging effects in Caenorhabditis elegans. Purified PE (100 μg/ml) dietary supplement was given to C. elegans and investigated for its anti-aging potential. PE treatment improved the mean life span of wild type (N2)-animals from 15±0.1 to 19.9±0.3 days. PE treatment also moderated the decline in aging-associated physiological functions like pharyngeal pumping and locomotion with increasing age of N2 worms. Moreover, PE treatment also enhanced the stress tolerance in 5-day-aged adults with increase in mean survival rate from 22.2±2.5 to 41.6±2.5 % under thermo stress and from 30.1±3.2 to 63.1±6.4 % under oxidative (hydrogen peroxide)-stress. PE treatment was also noted to moderate the heat-induced expression of human amyloid-beta(Aβ 1-42 ) peptide and associated paralysis in the muscle tissues of transgenic C. elegans CL4176 (Alzheimer's disease model). Effectiveness of PE in expanding the life span of mutant C. elegans, knockout for some up (daf-2 and age-1)-and down (daf-16)-stream regulators of insulin/IGF-1 signaling (IIS), shows the independency of PE effect from DAF-2-AGE-1-DAF-16 signaling pathway. Moreover, the inability of PE in expanding the life span of hsf-1 knockout C. elegans(sy441) suggests the dependency of PE effect on heat shock transcription factor (HSF-1) controlling AGE (2014) stress-induced gene expression. In conclusion, our results demonstrated a novel anti-aging activity of PE which conferred increased resistance to cellular stress resulting in improved life span and health span of C. elegans.

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Section: Introductionmentioning

confidence: 99%

Phycoerythrin extends life span and health span of Caenorhabditis elegans

Sonani

Singh²,

Awasthi

et al. 2014

AGE

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“…It is also used in the textile industry the sizing cotton yarn and also used as a gelling agent. Alginate is available in both forms that is acid and salt, the acid form of alginate is a linear polyuronic acid and it is called asalginic acid, whereas the salt form is an important cell wall component of brown seaweeds, consisting of 40% -47% dry weight of algal biomass [34] [50]. It has been reported that alginate is play an important role as a dietary fiber in human and animal both.…”

Section: Alginatementioning

confidence: 99%

Bioactive Compounds and Properties of Seaweeds—A Review

Pal¹,

Kamthania²,

Kumar³

2014

OALib

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In last three decades the discovery of metabolite and biological activities from macroalgae has been increased significantly. Many sophisticated modern research tools are available for making of chemical compound but there are still many natural bioactive compounds in the womb of nature which is a mystery, scientist are still working to find out more biologically active compounds. Bioactive substances from seaweeds currently receive the more attention from the pharmaceutical companies for the drug development as well as the researchers. Seaweeds are taking majority of attention from scientists because of its phenomenon bioactive compounds and its properties like anti-viral, anti-tumor, anti-inflammatory and anti-lipedimic and may more properties. This current review described mainly substances like metabolite, properties, and types of seaweeds. Emphasis is given to main metabolite and properties of seaweeds.

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“…There are three general forms (kappa, lambda and iota), each with their own gelling property. Kappa carrageenan today is almost exclusively obtained from farmed Kappaphycus alvarezii and iota from farmed Eucheuma denticulatum (Rasmussen and Morrissey 2007).…”

Section: Red Seaweeds and Carrageenansmentioning

confidence: 99%