Marine Sponge Derived Natural Products between 2001 and 2010: Trends and Opportunities for Discovery of Bioactives

Abstract

Marine sponges belonging to the phylum Porifera (Metazoa), evolutionarily the oldest animals are the single best source of marine natural products. The present review presents a comprehensive overview of the source, taxonomy, country of origin or geographical position, chemical class, and biological activity of sponge-derived new natural products discovered between 2001 and 2010. The data has been analyzed with a view to gaining an outlook on the future trends and opportunities in the search for new compounds and their sources from marine sponges.

Antimicrobial and anti-oxidant potentials of marine sponges of South Andaman, India

“…Recent studies have reported the isolation of novel anticancer, antiviral, antibacterial, antifungal, antiprotozoal, anthelmintic, anti-inflammatory, immunosuppressive, antifouling and a range of other bioactive compounds from marine species (Majali et al, 2015;El Amraoui et al, 2014;Mehbub et al, 2014). In the present study, the antimicrobial and anti-oxidant properties of seven marine sponges are described.…”

Anti-inflammatory, analgesic and antipyretic potentials of marine sponge Sigmadocia pumila

“…and Ircinia sp. were found to be the most promising genera because of their capacity for producing new bioactive compounds [12]. Considering this, the primary objective of the study was to detect the pharmaceutical applications of the marine sponge Sigmadocia pumila (S. pumila).…”

Antimicrobial, Antioxidant and Hemolytic Activity of Water-soluble Extract of Mottled Anemone Urticina crassicornis

“…Marine organisms are regarded as the largest unexplored source of bioactive compounds, and their biotechnological potential has resulted in extensive evaluation of their biological activities (Bhakuni and Rawat, 2006;Rocha et al, 2015;Suleria et al, 2015). However, the number of compounds isolated from marine organisms is heavily weighted in favor of lipid (or organic solvent)-soluble agents or compounds with medium polarity (Bhakuni and Rawat, 2006;Mehbub et al, 2014;Rocha et al, 2015). This might be due to the difficulties associated with the isolation and purification of water-soluble compounds.…”