Marine-sulfated polysaccharides extract of Ulva armoricana green algae exhibits an antimicrobial activity and stimulates cytokine expression by intestinal epithelial cells

Berri, Mustapha; Slugocki, Cindy; Olivier, Michel; Helloin, Emmanuelle; Jacques, Isabelle; Salmon, Henri; Demais, Hervé; Goff, Matthieu Le; Collén, Pi Nyvall

doi:10.1007/s10811-016-0822-7

Cited by 87 publications

(53 citation statements)

References 49 publications

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“…Sulfated polysaccharide extracts of the green seaweed Ulva armoricana have been reported to stimulate cytokine expression in intestinal epithelial cells and possess antimicrobial and immunomodulatory activities. These properties could be used to improve the resistance of farm animals to various types of infections (Berri et al., ). A fucoidan‐like polysaccharide extracted from Sargassum horneri has anti‐inflammatory activity toward lipopolysaccharide‐stimulated RAW 264.7 cells through the activation of NF‐κB, p50, p65, and p38, and the phosphorylation of extracellular signal‐regulated kinases.…”

Section: Seaweeds As Sources Of Novel Polysaccharides With Nutraceutimentioning

confidence: 99%

Nutraceutical Potential of Seaweed Polysaccharides: Structure, Bioactivity, Safety, and Toxicity

Tanna

Mishra

2019

Comp Rev Food Sci Food Safe

236

108

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In recent years, marine organisms including seaweeds have been highlighted as potential sources of useful metabolites and bioactive compounds, with vast biological and physiological activities. Seaweeds have long been used as a food source, for medicinal purposes, and as dietary supplements in various Asian countries, and their potential benefits have recently attracted the attention of many Western and European countries. Their commercial value depends on their applications in the food, nutraceutical, and pharmaceutical industries. Seaweeds are considered a potential source of nutraceuticals or functional foods, and analysis of taste‐oriented motives has revealed that seaweeds are preferentially selected over other types of marine foods by seafood consumers and people with high levels of health, education, and living status. It is a general perception that health conscious people prefer environmentally friendly food sources, and present an opportunity to focus on seaweed‐based foods, which have significant nutritional benefits to humans. Among the various bioactive constituents, seaweed polysaccharides have been proven to possess various beneficial properties including anticoagulant, anti‐inflammatory, antioxidant, anticarcinogenic, and antiviral activities. The diversity and composition of seaweed polysaccharides play vital roles in these biological activities. Seaweeds are a rich source of sulfated polysaccharides, which are responsible for much of the bioactivity, as they can interact with various textures and cellular proteins. A number of toxicological assays and clinical trials suggest that the ingestion of seaweeds as functional foods should be considered worldwide to improve immune responses. In this review, different polysaccharides from seaweeds and their compositions and potential nutraceutical applications are discussed.

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Section: Seaweeds As Sources Of Novel Polysaccharides With Nutraceutimentioning

confidence: 99%

Nutraceutical Potential of Seaweed Polysaccharides: Structure, Bioactivity, Safety, and Toxicity

Tanna

Mishra

2019

Comp Rev Food Sci Food Safe

236

108

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“…The variability of bioactive compounds in seaweeds influences the lab techniques used to obtain antimicrobials ranging from traditional extraction techniques, solid-liquid extraction or liquid-liquid extraction, to the most modern process of supercritical fluid extraction using CO2 ultrasonically-assisted extraction [93] The potential applications in aquaculture [94] and in the pharmaceutical and food industry [95], have been evaluated, while studies on food producing animals, and in pigs in particular, are limited. Berri et al [112] evaluated the effect of marine-sulfated polysaccharide extract from the green macroalga Ulva armoricana against seven bacterial strains found in pigs (Table 6).…”

Section: Sphaerane Bromoditerpenesmentioning

confidence: 99%

“…(0.18 g of laminarin and 0.34 g of fucoidan per kg of feed). A study using an in vitro system of porcine intestinal epithelial cells showed that ulvans from Ulva armoricana, a green seaweed, upregulated the gene expression of cytokines such as IL1α, IL1β, L6, IL8, TNFα [112,128].…”

Section: Anti-inflammatory Functionmentioning

confidence: 99%

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Seaweeds in Pig Nutrition

Corino

Modina

Giancamillo

et al. 2019

Animals

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Simple Summary: In pig nutrition, alternative and safe supplements are needed to enhance the pigs' health and welfare. Natural feed components, such as herbs and plant extracts, are of great importance in animal nutrition, and marine macroalgae can be considered as supplements positively influence animal health parameters. Seaweeds possess several bioactive molecules that are studied for their prebiotic, anti-microbial, antioxidant, anti-inflammatory and immunomodulatory effects. Seaweed benefits are related to their content of sulfated polysaccharides, phlorotannins, diterpenes, omega-3 polyunsaturated fatty acids, minerals and vitamins. This paper reviews the following biological functions of seaweeds and seaweed extracts in pig nutrition: prebiotics, anti-microbial, antioxidant, anti-inflammatory and immunomodulatory effects, promoting intestinal well-being and improving digestibility.Abstract: Seaweeds are macroalgae, with different sizes, colors and composition. They consist of brown algae, red algae and green algae, which all have a different chemical composition and bioactive molecule content. The polysaccharides, laminarin and fucoidan are commonly present in brown seaweeds, ulvans are found in green seaweeds and, red algae contain a large amount of carrageenans. These bioactive compounds may have several positive effects on health in livestock. In order to reduce the antimicrobials used in livestock, research has recently focused on finding natural and sustainable molecules that boost animal performance and health. The present study thus summarizes research on the dietary integration of seaweeds in swine. In particular the influence on growth performance, nutrients digestibility, prebiotic, antioxidant, anti-inflammatory, and immunomodulatory activities were considered. The review highlights that brown seaweeds seem to be a promising dietary intervention in pigs in order to boost the immune system, antioxidant status and gut health. Data on the use of green seaweeds as a dietary supplementation seems to be lacking at present and merit further investigation.(Bacillariophyceae), green algae (Chlorophyceae) and golden algae (Chrysophyceae) are the most abundant but blue-green algae (Cyanophyceae) are also defined as microalgae [2]. The bioactive molecules of microalgae are used as food and feed supplements [3].Seaweeds are marine organisms and comprise thousands of species, which are classified on the basis of their pigmentation: brown seaweeds (Phaeophyceae), red seaweeds (Rhodophyceae) and green seaweeds (Chlorophyceae).There are around 1800 species of brown seaweeds include, only 1% of which are recognized from freshwater and the size range varies from 20 m to 30 cm long. The brown color of these algae is related to the main content of carotenoid fucoxanthin, which masks β-carotene, violaxanthin, diatoxanthin, and chlorophyll. The main polysaccharides are laminarin, fucoidans and alginates, and the cell walls are composed of cellulose and alginic acid [4].Like brown seaweeds, red algae (about 6100 specie...

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“…Some find commercial applications in cosmetics and skin‐care products, emulsifiers, the food industry and medicine . Some sulfated polysaccharides in particular have remarkable medical applications …”

Section: Lipidsmentioning

confidence: 99%

Microalgae cultivation and metabolites production: a comprehensive review

Vuppaladadiyam

Prinsen

Raheem

et al. 2018

Biofuels Bioprod Bioref

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Microalgae have important potential in the bio‐based industry. However, their light‐utilization mechanisms are still not fully understood. Together with knowledge of their metabolic pathways and their responses in carbon partitioning to different primary metabolites (carbohydrates, lipids and proteins), this information is essential if their potential and profitability are to be better exploited. The first part of this review describes the techniques used for microalgae cultivation and the growth factors that determine their productivity, one of the most important factors in techno‐economic assessment studies of microalgae production systems. In the second part, a closer look is taken at their chemical composition in relation to the biosynthesis of primary and secondary metabolites. © 2018 Society of Chemical Industry and John Wiley & Sons, Ltd

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Marine-sulfated polysaccharides extract of Ulva armoricana green algae exhibits an antimicrobial activity and stimulates cytokine expression by intestinal epithelial cells

Cited by 87 publications

References 49 publications

Nutraceutical Potential of Seaweed Polysaccharides: Structure, Bioactivity, Safety, and Toxicity

Nutraceutical Potential of Seaweed Polysaccharides: Structure, Bioactivity, Safety, and Toxicity

Seaweeds in Pig Nutrition

Microalgae cultivation and metabolites production: a comprehensive review

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