Marital satisfaction is difficult to achieve because various problems arise after marriage, especially for wives living with their in-laws. The number of family members often has the potential to increase conflict between daughters and in-laws. Marital satisfaction can be affected by marital adjustment and self-disclosure. This study aims to determine the relationship between marital adjustment self-disclosure and marital satisfaction in wives who live with their parents-in-law simultaneously or partially. Using a correlational quantitative approach with 67 wives who lived with their parents-in-law for at least one year with a marriage age of 1-5 years and lived in Semarang as participants, Data were collected through the incidental sampling method from June 21, 2023, until June 27, 2023, using Google Form and multiple regression to analyze the data. The result showed a positive relationship between marital adjustment self-disclosure and marital satisfaction with the coefficient correlation value R = 0,882 with sig = 0,000 < 0,01, so the central hypothesis of this study is accepted with an influence of 77.8%. This study informs wives with in-laws to be more open and adjustable.