Markers of oxidative stress in fit, health-conscious elderly people living in the paris area

Mj, Cals; Succari, M; Meneguzzer, E.; Pontezière, C.; Pn, Bories; Devanlay, M; Desveaux, N; Gatey, M; Luciani, L; Blonde-Cynober, F.; Coudray‐Lucas, C.

doi:10.1016/s0899-9007(97)83054-7

Cited by 19 publications

(3 citation statements)

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“…The negligible difference in plasma Se (<1 ng/ml) between the two groups suggests that the results of the 1994–1995 survey in the elderly [ 87 ] may have been due to a nadir of Se intake and status in the UK at that time, rather than lower Se status in the elderly than in younger adults. The findings of similar Se status in both groups in the 2008–2012 NDNS [ 20 ] are in agreement with other studies, which suggest that apparently healthy elderly subjects have similar [ 88 , 89 ] or somewhat lower [ 90 ] Se status than younger adults.…”

Section: Changes In Selenium Intakes and Status In The Uksupporting

confidence: 92%

Vegetarianism and colorectal cancer risk in a low-selenium environment: effect modification by selenium status? A possible factor contributing to the null results in British vegetarians

Sobiecki

2017

Eur J Nutr

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BackgroundDespite the consistent findings of lower total cancer incidence in vegetarians than in meat-eaters in the UK, the results of studies of colorectal cancer (CRC) risk in British vegetarians have largely been null. This was in contrast to the hypothesis of a decreased risk of CRC in this population due to null intake of red and processed meats and increased intake of fibre. Although the data are inconsistent, it has been suggested that selenium (Se) status may influence CRC risk.MethodsA literature review was performed of studies on CRC risk in vegetarians, Se intakes and status in vegetarians, and changes of Se intakes and status in the UK throughout the follow-up periods of studies on CRC risk in British vegetarians.ResultsVegetarians in the UK and other low-Se areas were found to have low Se intakes and status compared to non-vegetarians. There was some evidence of a reverse J-shaped curve of Se intakes and status in the UK throughout the last three decades. These presumed patterns were followed by the changes in CRC mortality or incidence in British vegetarians during this period.ConclusionsAvailable data on Se intake and status in British vegetarians, as well as the relationship between their secular changes in the UK and changes in CRC risk in this dietary group, are compatible with the hypothesis that low Se status may contribute to the largely null results of studies of CRC risk in vegetarians in the UK.

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Section: Changes In Selenium Intakes and Status In The Uksupporting

confidence: 92%

Vegetarianism and colorectal cancer risk in a low-selenium environment: effect modification by selenium status? A possible factor contributing to the null results in British vegetarians

Sobiecki

2017

Eur J Nutr

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“…In multivariate analysis, age, sex, anthropometric factors, cardiovascular disease, and medication use did not impact TAS. In terms of age, the presented result is consistent with some other studies on the antioxidant potential [ 25 , 26 ]. Some research has presented a decrease with age in total plasma antioxidant capacity [ 27 , 28 ].…”

Section: Discussionsupporting

confidence: 92%

The Association of Oxidative and Antioxidant Potential with Cardiometabolic Risk Profile in the Group of 60- to 65-Year-Old Seniors from Central Poland

et al. 2022

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Pathogenesis of cardiovascular diseases is caused by, inter alia, oxidative stress. On the other hand, cardiovascular risk factors may cause redox imbalance. The pathological pathways between those components are to be determined. In the group comprised of 300 sex-matched subjects, we evaluated a number of cardiovascular risk factors: blood pressure, body mass, lipids, glucose, homocysteine, uric acid, von Willebrand factor (vWF), VCAM-1 and ICAM-1. The presence of cardiovascular diseases and drugs for their treatment were examined. Secondly, we assessed total antioxidative status (TAS), total oxidative status (TOS) and other markers of oxidative stress. TAS was inversely related to LDL cholesterol. TOS was positively associated with BMI and female sex, but negatively associated with the use of angiotensin II receptor antagonists. Plasma lipid peroxides concentration was positively related to ICAM-1 and presence of stroke, whereas platelet lipid peroxides were positively associated with vWF. Platelets proteins thiol groups were in a positive relationship with vWF, but in a negative relationship with uric acid and diagnosed lipid disorders. Both free thiol and amino groups were positively associated with plasma glucose. Platelets free amino groups were related to platelets count. Superoxide generation by blood platelets (both with and without homocysteine) was positively connected to glucose level. Among women, oxidative markers appear to be more related to glucose level, whereas among men they are related to body mass indices. TAS, TOS and oxidative markers are largely related to modifiable cardiovascular risk factors such as body mass, and intake of drugs such as angiotensin II receptor blockers. Plasma and platelet oxidation markers appear to be especially associated with glucose concentration. The presented analyses unanimously indicate strong connections between cardiovascular risk factors and redox potential and specify how cardiometabolic interventions may counter-balance oxidative stress.

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“…Mutations are, therefore, more likely to take place in the mitochondrial genome of differentiated cells [5]. Curiously, healthy elderly individuals can have oxidative stress levels that are similar to those of young adults [6], or at least comparable in terms of antioxidant defences [7]. This suggests that oxidation is not inevitable in aging.…”

Section: Introductionmentioning

confidence: 99%

Chrononutrition against Oxidative Stress in Aging

Garrido

Terrón

Rodríguez

2013

Oxidative Medicine and Cellular Longevity

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Free radicals and oxidative stress have been recognized as important factors in the biology of aging and in many age-associated degenerative diseases. Antioxidant systems deteriorate during aging. It is, thus, considered that one way to reduce the rate of aging and the risk of chronic disease is to avoid the formation of free radicals and reduce oxidative stress by strengthening antioxidant defences. Phytochemicals present in fruits, vegetables, grains, and other foodstuffs have been linked to reducing the risk of major oxidative stress-induced diseases. Some dietary components of foods possess biological activities which influence circadian rhythms in humans. Chrononutrition studies have shown that not only the content of food, but also the time of ingestion contributes to the natural functioning of the circadian system. Dietary interventions with antioxidant-enriched foods taking into account the principles of chrononutrition are of particular interest for the elderly since they may help amplify the already powerful benefits of phytochemicals as natural instruments with which to prevent or delay the onset of common age-related diseases.

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Markers of oxidative stress in fit, health-conscious elderly people living in the paris area

Cited by 19 publications

References 0 publications

Vegetarianism and colorectal cancer risk in a low-selenium environment: effect modification by selenium status? A possible factor contributing to the null results in British vegetarians

Vegetarianism and colorectal cancer risk in a low-selenium environment: effect modification by selenium status? A possible factor contributing to the null results in British vegetarians

The Association of Oxidative and Antioxidant Potential with Cardiometabolic Risk Profile in the Group of 60- to 65-Year-Old Seniors from Central Poland

Chrononutrition against Oxidative Stress in Aging

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