Maslinic acid as a feed additive to stimulate growth and hepatic protein-turnover rates in rainbow trout (Onchorhynchus mykiss)

Apolipoprotein E determines the hepatic transcriptional profile of dietary maslinic acid in mice

“…With our experimental design, animals consuming the MAenriched OO diet received an approximate dose of 1.5 mg/kg as functional food. This dose is much lower than the 25-mg/ kg dose reported to induce DNA and hepatic hyperplasia in trout [35,36]. Due to the dose or the animal model, we have not observed any of the changes reported by these authors, such as cell packaging, decrease in sinusoidal spaces and cell size changes.…”

Maslinic Acid Reduces Blood Glucose in KK-Ay Mice

“…We have previously reported that maslinic acid and related pentacyclic triterpenes represent a new class of inhibitors of glycogen phosphorylase, and their glucose-lowering activity in diabetic mice induced by adrenaline might be due to, at least in part, modulation hepatic glycogen metabolism. 3,4) Very recently, Fernandez-Navarro et al 9) reported that maslinic acid exhibited modulation effects of on hepatic glycogen metabolism in the rainbow trout, and claimed that their observation was in agreement with our findings.…”

Maslinic acid in olive fruit alleviates mild knee joint pain and improves quality of life by promoting weight loss in the elderly

“…(19,20) We consider that MA is likely to be an effective therapy against sarcopenia or loss of skeletal muscle mass and function. (21) From these discussions, MA in olive fruit extract is a potential food ingredient that can support in the eradication of “locomotive syndrome” defined by the JOA such as osteoarthritis and muscle deterioration.…”