Mass cytometry imaging in physiology

Subcellular physiology

“…10 Pohl et al 11 highlight the need for comprehensive characterization of cellular marker profiles to enable unbiased screening for the determination of cell identity, as exemplified on endothelial cells and their plasticity in renal disease. Shi et al 12,13 recently described a novel approach to physiological mass cytometry imaging, that is, a spatial analysis workflow to enable multiplex imaging data analysis to study cardiac post-infarction injury. Yeh et.…”

Color in physiology

“…17 Incorporating diverse data types such as images, genomic sequences, and clinical records demands sophisticated visualization tools capable of capturing complex relationships and patterns across modalities, in which color coding and colored visualization can aid greatly. Standardization and color coding facilitate clarity and consistency in multiplex analyses, 18,19 streamlining data interpretation and enhancing reproducibility across biomedical research, thereby fostering efficient collaboration and advancing scientific understanding.…”