Abstract-As a relevant communication structure for integrated circuits, Network-on-Chip (NoC) architecture has attracted a range of research topics. Compared to conventional bus technology, NoC provides higher scalability and enhances the system performance for future System-on-Chip (SoC). Divergently, we presented the packet-switching router design for 2D NoC which supports 2D mesh topology. Despite the offered benefits compared to conventional bus technology, NoC architecture faces some limitations such as high cost communication, high power consumption and inefficient router pipeline usage. One of the proposed solutions is 3D design. In this context, we suggest router architecture for 3D mesh NoC, a natural extension of our prior 2D router design. The proposal uses the wormhole switching and employs the turn mod negativefirst routing algorithm Thus, deadlocks are avoided and dynamic arbiter are implemented to deal with the Quality of Service (QoS) expected by the network. We also adduce an optimization technique for the router pipeline stages. We prototyped the proposal on FPGA and synthesized under Synopsys tool using the 28 nm technology. Results are delivered and compared with other famous works in terms of maximal clock frequency, area, power consumption and estimated peak performance.