2020
DOI: 10.1002/smll.202000462
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Massively Multiplexed Submicron Particle Patterning in Acoustically Driven Oscillating Nanocavities

Abstract: high-throughput particle manipulation for preparation, enrichment, and quality control. For example, the size distribution of synthesized nanoparticle catalysts determines their catalysis efficiency. [7,8] In biomedical applications, exosomes, which are submicron extracellular vesicles [9][10][11] containing DNA, microRNAs, and proteins, are a potential source of diagnostic biomarkers. [12][13][14][15] Suitable nanoparticle manipulation tools would enable sizebased sorting/filtering, or manipulation toward dow… Show more

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Cited by 39 publications
(20 citation statements)
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“…The small dimensions characteristic of microfluidic devices has enabled selective manipulation of similarly small objects such as cells and microparticles (Lee et al 2017;Di Carlo 2009;Tayebi et al 2020), including for tissue engineering (Choi et al 2007; Andersson and van den Berg 2004; Khademhosseini et al 2006;Novak et al 2020;Bhatia and Ingber 2014), cell-cell interaction and signalling studies (Regehr et al 2009;Faley et al 2008;Zervantonakis et al 2011), sample concentration and sorting (Ding et al 2012;Gascoyne and Vykoukal 2002;Ahmed et al 2018). This accurate and versatile manipulation of biological matter is essential for many lab-on-a-chip platforms, especially those designed for diagnostic purposes.…”
Section: Introductionmentioning
confidence: 99%
See 1 more Smart Citation
“…The small dimensions characteristic of microfluidic devices has enabled selective manipulation of similarly small objects such as cells and microparticles (Lee et al 2017;Di Carlo 2009;Tayebi et al 2020), including for tissue engineering (Choi et al 2007; Andersson and van den Berg 2004; Khademhosseini et al 2006;Novak et al 2020;Bhatia and Ingber 2014), cell-cell interaction and signalling studies (Regehr et al 2009;Faley et al 2008;Zervantonakis et al 2011), sample concentration and sorting (Ding et al 2012;Gascoyne and Vykoukal 2002;Ahmed et al 2018). This accurate and versatile manipulation of biological matter is essential for many lab-on-a-chip platforms, especially those designed for diagnostic purposes.…”
Section: Introductionmentioning
confidence: 99%
“…The relative strengths of these forces depends on the channel design, frequency of operation, fluid and particle properties, and the nature of the sound field (Muller et al 2012;Settnes and Bruus 2012). In these systems, acoustic streaming dictates the minimum collectable particle size, with it having a far greater effect on disrupting the trajectories of particles towards a stable end location than Brownian motion (Tayebi et al 2020).…”
Section: Introductionmentioning
confidence: 99%
“…Acoustofluidics, which integrates acoustic waves with microfluidics to manipulate particles and fluids in microscale fluid, has been widely used in material engineering [ 1 , 2 , 3 ] and biotechnology [ 4 , 5 ], due to the advantages of noncontact, better biocompatibility, and compactness [ 6 ]. Surface acoustic waves (SAWs), which are generated and propagated on the surface, have attracted attention for the following reasons.…”
Section: Introductionmentioning
confidence: 99%
“…Especially for sub−micrometer particles, optical trapping opens up avenues for quantum science [2][3][4][5] in studying quantum phenomena [6] and transduction applications [7]. Generally, trapping and manipulation of sub−micrometer particles have been demonstrated by using optical dipoles or gradient forces, traveling surface acoustic waves [8], dielectrophoretic forces [9], surface plasmonics [10], Joule heating effects [11], and optical standing waves [12]. Using the optical gradient forces, conventional optical tweezers (OT) relying on highly focused laser beams are the most commonly used approach to trap and manipulate sub−micrometer particles in various studies, such as the physical [13][14][15] and biomechanical [16,17] research.…”
Section: Introductionmentioning
confidence: 99%