2014
DOI: 10.1016/j.fsigen.2014.03.014
|View full text |Cite
|
Sign up to set email alerts
|

Massively parallel pyrosequencing of the mitochondrial genome with the 454 methodology in forensic genetics

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
2
1
1

Citation Types

1
21
2

Year Published

2014
2014
2018
2018

Publication Types

Select...
8
2

Relationship

2
8

Authors

Journals

citations
Cited by 40 publications
(24 citation statements)
references
References 27 publications
1
21
2
Order By: Relevance
“…13 In this study, 145 whole mtGenomes from unrelated Chinese Han population were sequenced using the Ion PGM System. Concordance testing obtained complete consistency between the PGM and STS data, excluding the number of Cs in the homopolymeric stretches around positions 303-316 and 16 184-16 193, similar to the results reported by Parson et al, 13 Mikkelsen et al, 14 Seo et al 15 and McElhoe et al 16 Thus, sequence data from positions 303-316 and 16 184-16 193 for all the 145 samples were verified using STS in this study.…”
Section: Resultssupporting
confidence: 89%
“…13 In this study, 145 whole mtGenomes from unrelated Chinese Han population were sequenced using the Ion PGM System. Concordance testing obtained complete consistency between the PGM and STS data, excluding the number of Cs in the homopolymeric stretches around positions 303-316 and 16 184-16 193, similar to the results reported by Parson et al, 13 Mikkelsen et al, 14 Seo et al 15 and McElhoe et al 16 Thus, sequence data from positions 303-316 and 16 184-16 193 for all the 145 samples were verified using STS in this study.…”
Section: Resultssupporting
confidence: 89%
“…However, as predicted nearly five years ago [10], massively parallel sequencing technologies (MPS) are now finding their way into the forensic arena [8,[11][12][13][14][15][16][17][18][19][20]. These technologies largely remove the greatest existing technical and cost barriers to mtGenome sequencing of low DNA quality and quantity specimens.…”
Section: Introductionmentioning
confidence: 99%
“…Another limitation of Sanger sequencing is that samples composed of mixtures cannot be readily deconvolved because the output is not quantitative [38]. Massively parallel sequencing (MPS) has made it possible to expand sequencing to cover the entire mitochondrial genome in a more effective, more quantitative, less laborious, and far less costly manner [12, 3941]. Moreover, whole-mitochondrial genome sequencing reduces error in haplogroup assignment [40], which in turn improves understanding of the evolutionary history of humans.…”
Section: Introductionmentioning
confidence: 99%