Recent large-scale operations, including frequent maritime transportation and unauthorised as well as unlawful collisions of drainage wastes, have polluted the ocean’s ecology. Due to the ocean’s unsuitable ecology, the entire globe may experience drastic aberrant conditions, which will force illness onto all living things. Therefore, an advanced system is very necessary to remove the undesired waste from the ocean’s surface and interior. Through the use of progressive unmanned amphibious vehicles (UAV), this study provides a dynamic operational mode-based solution to damage removal. In order to successfully handle the heavy payloads of ravage collections when the UAV reveals centre of gravity concerns, a highly manoeuvrable-based design inspired by nature has been imposed. The ideal creatures to serve as the inspiration for this piece are tropical birds, which have a long tail for navigating tricky situations. The design initialization was carried out by focusing on the outer body of tropical birds. Following this, special calculations were conducted and the full design parameters of the UAV were established. This study proposes a unique mathematical formulation for the development of primary and secondary design parameters of an UAV. The proposed mission profile of this application is computationally tested with the aid of sophisticated computational methodologies after the modelling of this UAV. The computational methods that are required are one-way coupling-based hydro-structural interaction assessments and computational hydrodynamic analyses. Computing is used to determine the aerodynamic and hydrodynamic forces over the UAV, the lightweight materials to withstand high fluid dynamic loads, and the buoyancy forces to complete the UAV components. These computational methods have been used to produce a flexible and fine-tuned UAV design for targeted real-time applications.