The concrete-filed square steel tube with inner I-shaped CFRP profiles short columns under bi-axial eccentric load were investigated by the finite element analysis software ABAQUS. The working mechanism of the composite columns which is under bi-axial eccentric load are investigated by using the stress distribution diagram of steel tube concrete and the Ishaped CFRP profiles. In this paper, the main parameters; eccentric ratio, steel ratio, steel yield strength, concrete compressive strength and CFRP distribution rate of the specimens were investigated to know the mechanical behavior of them. The interaction between the steel tube and the concrete interface at different characteristic points of the composite columns were analyzed. The results showed that the ultimate bearing capacity of the concrete-filed square steel tube with inner I-shaped CFRP profiles short columns under biaxial eccentric load decrease with the increase of eccentric ratio, the ultimate bearing capacity of the composite columns increase with the increase of steel ratio, steel yield strength, concrete compressive strength and CFRP distribution rate. The contact pressure between the steel tube and the concrete decreased from the corner zone to the flat zone, and the contact pressure decreased from the mid-height cross section to other sections.