Maternal and fetal characteristics for predicting risk of Cesarean section following induction of labor: pooled analysis of <scp>PROBAAT</scp> trials

Quach, Diane; Eikelder, M. ten; Jozwiak, Marta; Davies‐Tuck, Miranda; Bloemenkamp, Kitty W. M.; Mol, Ben W.; Li, Wentao

doi:10.1002/uog.24764

Cited by 20 publications

(20 citation statements)

References 29 publications

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“…However, we are a tertiary referral center dealing with higher‐risk profile cases. In addition, our trial inclusion criteria included exclusively nulliparous women with initially unfavorable cervices 17 and obstetric indication for labor induction such as diabetes, “nonreassuring fetal status (albeit with reassuring fetal heart rate tracing),” hypertension or large for dates, 18 and overweight‐obese 19 , which are all risk factors for cesarean delivery after failed labor induction.…”

Section: Discussionmentioning

confidence: 99%

Early versus delayed amniotomy with immediate oxytocin after Foley catheter cervical ripening in nulliparous labor induction: A randomized trial

Hasan

Hong

Teo

et al. 2022

Intl J Gynecology & Obste

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Objective: To evaluate immediate oxytocin and early amniotomy compared with delayed amniotomy after Foley catheter cervical ripening in nulliparous women on intervention-to-delivery interval.Methods: A randomized trial was conducted from September 2020 to March 2021.A total of 140 term nulliparas (70 early amniotomy, 70 delayed amniotomy) with Foley catheter-ripened cervices (dilatation ≥3 cm achieved), singleton fetus, cephalic presentation with intact membranes, and reassuring fetal heart rate tracing were recruited. Women were randomized to immediate titrated intravenous oxytocin infusion and early amniotomy or delayed amniotomy (after 4 h of oxytocin). The primary outcome was intervention (oxytocin)-to-delivery interval (h).Results: Intervention-to-delivery intervals (h) were mean ± standard deviation 9.0 ± 3.6 versus 10.6 ± 3.5 h (mean difference of 1.4 h) (P = 0.004) for the early versus delayed amniotomy arms, respectively. Birth rates at 6 h after oxytocin infusion were 19 of 70 (27.1%) versus 8 of 70 (11.4%) (relative risk, 2.38 [95% confidence interval (CI), 1.11-5.06]; number needed to treat: 7 [95% CI, 3.5-34.4]) (P = 0.03), cesarean delivery rates were 29 of 70 (41.4%) versus 33 of 70 (47.1%) (relative risk, 0.88; 95% CI, 0.61-1.28) (P = 0.50), and maternal satisfaction on birth process were a median of 7 (interquartile range, 7-8) versus 7 (interquartile range, 7-8) (P = 0.40) for the early versus delayed amniotomy arms, respectively. Conclusion:In term nulliparas with cervices ripened by Foley catheter, immediate oxytocin and early amniotomy compared with a planned 4-h delay to amniotomy shortened the intervention-to-delivery interval but did not significantly reduce the cesarean delivery rate.

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Section: Discussionmentioning

confidence: 99%

Early versus delayed amniotomy with immediate oxytocin after Foley catheter cervical ripening in nulliparous labor induction: A randomized trial

Hasan

Hong

Teo

et al. 2022

Intl J Gynecology & Obste

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“…To our excellent knowledge, the publication about the efficacy of dinoprostone vaginal insert in cervical ripening in the term pregnancy with oligohydramnios has remained limited. Especially, influencing factors relative to successful cervical ripening (SCR) have been differently described from this study to another study 15–18 . Thus, we conducted this study to evaluate the effectiveness, safety, and success rate of dinoprostone 10 mg controlled‐release vaginal insert as well as finding some factors attributable to SCR at our center.…”

Section: Introductionmentioning

confidence: 93%

“…Especially, influencing factors relative to successful cervical ripening (SCR) have been differently described from this study to another study. [15][16][17][18] Thus, we conducted this study to evaluate the effectiveness, safety, and success rate of dinoprostone 10 mg controlled-release vaginal insert as well as finding some factors attributable to SCR at our center.…”

Section: Introductionmentioning

confidence: 99%

Using dinoprostone slow release vaginal insert for cervical ripening in term‐pregnancy with oligohydramnios

Nguyen

Vuong

Nguyen

et al. 2023

J of Obstet and Gynaecol

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The study purposed to evaluate the success rate of cervical ripening using dinoprostone controlled-release vaginal insert and reveal some factors relating to successful cervical ripening. Methods: This cross-sectional study was conducted at Tu Du Hospital in Vietnam from December 2021 to August 2022. The study enrolled 200 pregnant women with gestational age ≥37 weeks diagnosed with oligohydramnios. These candidates underwent dinoprostone cervical ripening (DCR) according to the local protocol. The Bishop score ≥7 after 24 h was determined for the successful cervical ripening (SCR). Results: In total, the success rate of DCR achieved at 57.5% and the cesarean delivery rate was 46.5%. None of the severe side-effects and complications was present. Using multivariable logistic regression, the study found that the body mass index ≥25 kg/m 2 and oxytocin infusion drip related to SCR with adjusted odds ratio (aOR): 3.67 (95% confidence intervals [CI]: 1.78-7.57) and aOR: 4.68 (95% CI: 1.84-11.93), p < 0.001. Using the Kaplan-Meier curve, the present study revealed a significant difference between Bishop <3 and ≥3 following the duration time of cervical ripening, with hazard ratio: 1.38 (95% CI: 1.19-1.59), p < 0.001. The time duration of cervical ripening was not significantly different following amniotic fluid index from 3 to 5 cm. Conclusions: Cervical ripening using a dinoprostone vaginal insert is a potentially acceptable method in term pregnancy accompanying with oligohydramnios. The probability of SCR can be predicted on a careful assessment of relative factors by obstetricians. Further studies are required to strengthen these findings.

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“…Cervical status, parity, body mass index (BMI), gestational age, and estimated fetal weight affect the success of IOL [ 9 , 10 ]. The most important predictor for successful IOL is the pre-induction cervical status.…”

Section: Introductionmentioning

confidence: 99%

Prediction model for successful induction of labor by cervical strain elastography diagnosed at late-term pregnancy in nulliparous women: a prospective cohort study

Yang

Zhou

Chen

et al. 2023

BMC Pregnancy Childbirth

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Background The use of cervical strain elastography for nulliparous women during late-term pregnancy remains unclear. This study assesses the predictive value of late-term cervical strain elastography for successful induction of labor (IOL) in nulliparous women. Methods This single-centered, prospective study included 86 patients undergoing IOL between January 2020 and March 2022. Univariate and multivariate analyses were conducted to identify predictive factors for successful IOL. The predictive values were assessed using the area under receiver operating characteristic (ROC) curves. Results IOL was successful in 58 patients. The hardness ratio and cervical length were significantly associated with successful late-term IOL in nulliparous women. The predictive value of the combination of hardness ratio and cervical length was higher than that of cervical length alone. Conclusions The hardness ratio and cervical length assessed by cervical strain elastography during late-term pregnancy are predictors of the success of IOL in nulliparous women. The predictive value of the combination of hardness ratio and cervical length was higher than that of cervical length alone.

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Maternal and fetal characteristics for predicting risk of Cesarean section following induction of labor: pooled analysis of PROBAAT trials

Cited by 20 publications

References 29 publications

Early versus delayed amniotomy with immediate oxytocin after Foley catheter cervical ripening in nulliparous labor induction: A randomized trial

Early versus delayed amniotomy with immediate oxytocin after Foley catheter cervical ripening in nulliparous labor induction: A randomized trial

Using dinoprostone slow release vaginal insert for cervical ripening in term‐pregnancy with oligohydramnios

Prediction model for successful induction of labor by cervical strain elastography diagnosed at late-term pregnancy in nulliparous women: a prospective cohort study

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