Maternal and fetal outcomes of the pregnant woman with COVID-19: The first case report in Taiwan

Wang, Le Ming; Lai, Shiue‐Wei; Liang, So Jung; Yang, Szu Ting; Liu, Chia-Hao; Wang, Peng Hui

doi:10.1016/j.tjog.2021.07.045

Cited by 10 publications

(16 citation statements)

References 16 publications

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“…1,9–14 All emphasize an urgent need of national or international recommendations and guidelines to optimize prevention and management strategies for COVID-19 in pregnancy. 9,13,14 The healthcare team should help pregnant women to minimize the risk of SARS-CoV-2 infection and provide an adequate counseling and optimal medical service for those pregnant women, regardless of whether they have SARS-CoV-2 infection or not. 13,14…”

Section: Introductionmentioning

confidence: 99%

The impact of COVID-19 in pregnancy: Part II. Vaccination to pregnant women

Wang

Lee

Yang

et al. 2021

Journal of the Chinese Medical Association

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Effective strategies are urgently needed to decrease the risk of untoward outcomes of pregnant women with severe acute respiratory syndrome coronavirus 2 (coronavirus disease 2019 [COVID-19]) infection. Pregnant women are a vulnerable population to infectious disease pandemics with dramatically increased infectious diseases-related serious complications, such as the need of hospitalizations, the need of admission to intensive care unit, and the final disease-related death compared with those nonpregnant counterparts or those pregnant women without infection. Several studies have shown that vaccinations in pregnancy are a safe and highly effective strategy, not only for pregnant women but also for fetus and/or newborn because of the passive transplacental transfer of antibodies to the offspring. Active and passive prevention of infectious diseases is approved as effective strategies for women who attempt to become pregnant or during pregnancy. Despite the large and proven scientific evidence, pregnant women still puzzle over whether they should get vaccinated. The question therefore arises: Why are pregnant women so reluctant to receive vaccination? The explanation is more likely in the way that the benefits of vaccination have been communicated “confusedly.” In fact, like virtually all clinical trials, all the COVID-19 vaccine trials have excluded pregnant and lactating women from participating, contributing to uncertainty of safety and efficacy in COVID-19 vaccines that have been well prepared and available for the general adult population worldwide. Moreover, messenger RNA vaccine is a relatively brand-new vaccine, and experience with this type of vaccine is still scarce. It is hard to overcome this innovation deadlock. The knowledge and awareness of pregnant women who are at risk, and full information on the knowledge of vaccines and related preventable diseases in pregnant women may avoid hesitancy and increase vaccine acceptance. The current review is a part two addressing the impact of COVID-19 on pregnant women. We focus on the up-to-date information about the application of vaccination on pregnant women, especially during this COVID-19 pandemic.

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Section: Introductionmentioning

confidence: 99%

The impact of COVID-19 in pregnancy: Part II. Vaccination to pregnant women

Wang

Lee

Yang

et al. 2021

Journal of the Chinese Medical Association

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“…4 However, pregnant women with COVID-19 are more like to develop severe illnesses, compared to both nonpregnant women and pregnant women without COVID-19. 5 Pregnancy outcomes vary by trimester of presentation. 6 The risks of spontaneous abortion and preterm birth may not increase but there is a possibility of vertical transmission when it manifests during the third trimester of pregnancy.…”

Section: Introductionmentioning

confidence: 99%

Fetomaternal outcome of pregnancy with COVID-19: a prospective study in a COVID dedicated hospital

Begum¹,

Alam²,

Rehnuma³

et al. 2023

Int J Reprod Contracept Obstet Gynecol

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Background: Given physiological changes in immunological, pulmonary, cardiac, and coagulation systems during pregnancy, pregnant women have long been recognized as susceptible demographic during infectious disease pandemics. Learning about pregnancy outcomes, possible issues, and neonatal health issues in babies delivered to COVID-19-infected mothers is crucial. Study aimed to analyze fetomaternal outcome of pregnancy with COVID-19. Methods: This was a prospective longitudinal study done on COVID dedicated to Sylhet Shahid Shamsuddin Ahmed Hospital, from January 2021 to January 2022. A total of 54 pregnant women admitted with confirmed COVID-19 were included in this study as per inclusion criteria. Results: In this study, most patients were in the 26-33 age group (37.03%), followed by 18-25 age group (33.33%) and 24-40 age group (29.62%). 50% were primigravida. SARS COV-2 infection occurred in 51.85% of pregnant women in the 3rd trimester, 35.18% in the 2nd trimester, and 12.96% in the 1st trimester, 53.7% of patients had a mild case, 9.26% had moderate, and 37.04% had severe symptoms. 12.96% of patients needed ventilation, while 5.56% were in ICU without ventilation but on HFNC. Two patients had 1st-trimester abortion, and three had pre-term delivery. There was one IUFD, ongoing pregnancy in five patients, vaginal delivery in nine patients, and cesarean section in 25 patients. Sepsis occurred in 3.7% of patients, and post-partum hemorrhage in 1.85%. Oxygen was needed for 37.04% of patients with severe pneumonia. Out of 54 patients, 88.88% recovered, and 11.11% died in the hospital. The number of healthy babies was 74.07%, while premature babies were 5.56%, and there were two perinatal deaths. Conclusions: This study concluded that pregnant women with COVID-19 infection are at increased risk of adverse pregnancy and birth outcomes however, a low risk of congenital transmission, and the neonatal outcome was good. The availability of ICU in critical conditions is needed for better pregnancy outcomes.

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“…First, as shown by title of their article as “maternal outcome of selective feticide due to fetal anomaly in late trimester,” however, the authors did not really evaluate the maternal outcome after selective feticide. The definition of the evaluated item of “maternal outcome” was even absent in their study, although “maternal outcome” is a very simple and widely used item found everywhere, 5–7 contributing to total absence of results addressing maternal outcome in their study. As predicted, selective feticide extremely rarely results in maternal death (no maternal death was reported in their study); however, morbidity may be really followed after feticide.…”

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confidence: 97%