Maternal and neonatal outcome in cases of premature rupture of membranes beyond 34 weeks of gestation

Abstract

Background: Preterm premature rupture of membrane (PPROM) and premature rupture of membrane (PROM) are associated with various maternal and neonatal complications. Management guidelines regarding rupture of membrane before labour is still controversial. The study was carried out to determine the various maternal and neonatal outcomes associated with rupture of membranes beyond 34 weeks of gestation.Methods: It was a prospective observational study carried out in a tertiary care teaching hospital for a period of one year. All the pregnant women with rupture of membrane beyond 34 weeks are included in the study. After establishment of diagnosis of rupture of membranes, antibiotics were started and all of them were induced after 6 hours if they did not have spontaneous labour. Various maternal and neonatal outcomes were noted and statistical analysis carried out.Results: Incidence of rupture of membrane in our study was 4.2%. 92% of patients delivered within 24 hours of rupture of membrane and 18% of them required caesarean section. 5 neonates had respiratory distress syndrome and 1 neonate had sepsis.Conclusions: Induction of labour and delivery within 24 hours of rupture of membranes associated with low incidence of maternal and neonatal adverse outcome.

Outcome of neonates born to mothers with premature rupture of membranes

“…Similar results were seen in a study by Idrisia et al 11 where 79.5% were lower socioeconomic class cases and in in a study by Chhangetae et al 12 where 54% were lower socioeconomic class cases. However, in a study by Sharma et al 13 56.9% were middle socioeconomic class cases, which is contrary to our findings. It is observed in present study that PROM was high in cases of low socioeconomic status (70%) which might be due to poor nutritional status, anaemia and increased genitourinary infections due to poor personal hygiene.…”

“…The incidence of PROM >18 hrs duration in mothers in our hospital was 1.17%. This was similar to the incidence rate of 1.3% in a study by Idrisia et al 11 , but lower than the 2.7% incidence rate in the study by Alam et al 17 , and the 4.2% incidence rate in the study by Sharma et al 13 .…”

“…A study by Lokhande et al 19 had a mortality of 1.7% and a study by Mohan S, et al 21 had a mortality of 2.9% which are similar to the mortality in our study. However, the mortality was 5% in studies by Sharma et al 13 and Ramesh TV et al 16 which could be attributed to the inclusion criteria as they have included neonates whose mother had a history of PROM for more than 18 hours. In the study by Poovathi et al 22 the mortality was 10% and this could be due to the inclusion of only preterm neonates in their study.…”

A study of perinatal outcome in preterm premature rupture of membranes

“…12,13 In our study neonatal mortality is 10%, most common in neonataes delivered between 28-30wks of gestation that is early PPROM ( Table 9). 14,15 CONCLUSION PPROM was more common in younger age group, low socio-economic class and pimigravidae in present study. PPROM was not associated with previous history, booked or un booked and previous abortion.…”

Neonatal Outcomes in High Risk Pregnancies in an Egyptian Tertiary Health Care Center

“…Premature rupture of membranes (PROM); rupture of membranes before onset of labor and preterm premature rupture of membranes; rupture before 37 completed weeks, are associated with high perinatal as well as maternal morbidity [13] . Deleterious effects of PROM include chorioamnionitis, cord prolapse, placental abruption and preterm labor leading to various fetal complications like fetal death, neonatal pulmonary hypoplasia, RDS, neonatal sepsis, and intraventricular hemorrhage [14,15] .…”