Maternal Depression, Child Temperament, and Early-Life Stress Predict Never-Depressed Preadolescents’ Functional Connectivity During a Negative-Mood Induction

Liu, Pan; Vandermeer, Matthew R. J.; Ali, Ola Mohamed; Daoust, Andrew R.; Joanisse, Marc F.; Deanna, M; Hayden, Elizabeth P.

doi:10.1177/21677026211016419

Cited by 6 publications

(4 citation statements)

References 75 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Moreover, many studies investigated the differences in functional connectivity patterns between the amygdala and other brain regions in high-risk populations. Some studies reported that the amygdala had decreased functional connectivity between the PFC and ACC while assessing emotional faces, 89 while others have reported increased functional connectivity between the amygdala and several brain regions such as the ACC and PFC while assessing emotional faces, and during negative mood induction 90,91 . Thus, high-risk individuals display alterations in the functional connectivity of the amygdala during emotion processing; however, further studies are needed to understand the nature of this impairment and whether it is associated with participants’ resilience 82,91,92 …”

Section: Resultsmentioning

confidence: 99%

“…Some studies reported that the amygdala had decreased functional connectivity between the PFC and ACC while assessing emotional faces, 89 while others have reported increased functional connectivity between the amygdala and several brain regions such as the ACC and PFC while assessing emotional faces, and during negative mood induction. 90,91 Thus, high-risk individuals display alterations in the functional connectivity of the amygdala during emotion processing; however, further studies are needed to understand the nature of this impairment and whether it is associated with participants' resilience. 82,91,92 While retrieving self-referent emotional words, high-risk and low-risk twins showed no difference in the activation of the hippocampus; however, high-risk twins were biased towards retrieving a greater number of negative words.…”

Section: Functional Mri Studiesmentioning

confidence: 99%

See 1 more Smart Citation

Structural and Functional Brain Alterations in Populations with Familial Risk for Depression: A Narrative Review

Burhanoglu

Gönül

2022

Harv Rev Psychiatry

View full text Add to dashboard Cite

Learning objectivesAfter completing this activity, practitioners will be better able to:• Discuss the association between brain alterations and vulnerability or resilience to MDD in people with familial risk• Define how structural and functional brain alterations associated with vulnerability or resilience could lead to a better understanding of the pathophysiology of MDDAimFamilial history is associated with an increased risk for major depressive disorder (MDD). Despite the increased risk, some members of the familial high-risk population remain healthy, that is, resilient. Defining the structural and functional brain alterations associated with vulnerability or resilience could lead to a better understanding of the pathophysiology of MDD. This study aimed to review the current literature and discuss the association between brain alterations and vulnerability or resilience to MDD in people with familial risk.MethodsA literature search on MRI studies investigating structural and functional alterations in populations at familial risk for MDD was performed using the PubMed and SCOPUS databases. The search was conducted through June 13, 2022.ResultsWe reviewed and summarized the data of 72 articles (25 structural MRI, 35 functional MRI, 10 resting-state fMRI, one structural/functional MRI combined, and one structural/functional/resting-state fMRI combined). These findings suggested that resilience in high-risk individuals is related to the amygdala structure, frontal lobe activity, and functional connectivity between the amygdala and multiple frontal regions.ConclusionResilient and vulnerable individuals exhibit structural and functional differences in multiple frontal and limbic regions. However, further systematic longitudinal research incorporating environmental factors is required to validate the current findings.

show abstract

Section: Resultsmentioning

confidence: 99%

Section: Functional Mri Studiesmentioning

confidence: 99%

Structural and Functional Brain Alterations in Populations with Familial Risk for Depression: A Narrative Review

Burhanoglu

Gönül

2022

Harv Rev Psychiatry

View full text Add to dashboard Cite

show abstract

“…This is probably due to the fact that negative emotionality is more heterogeneous and has distinct facets that are differentially associated with different development outcomes of infants. For example, infant temperamental sadness is closely related to infant socioemotional development (Abramson et al, 2019; Liu et al, 2022). And infants' temperamental sadness uniquely predicts children's socioemotional development.…”

Section: Discussionmentioning

confidence: 99%

The effect of maternal empathy on infants’ attachment security: Moderation by maternal emotion regulation and infant temperament

Cheng

Ruan

et al. 2023

PsyCh Journal

View full text Add to dashboard Cite

This study examined the relationship between maternal empathy and infants’ attachment security and tested the moderating effects of maternal emotion regulation and infant negative emotional temperament. Participants were sampled from 215 families whose infants were 6 months old (T1) and from 170 families of the same cohort whose infants were 14 months old (T2). At T1, mothers were measured for their empathy (empathic concern and perspective taking), emotion regulation (reappraisal and suppression), and infant negative emotional temperament (sadness, falling reactivity, fear, and distress to limitations). At T2, mothers were again measured for their emotion regulation, and infant attachment was measured using the Strange Situation Procedure. Maternal empathic concern (EC) and perspective taking (PT) were found to be positively related to infant attachment security, while maternal reappraisal and infant temperamental sadness moderated the relationship between maternal PT and infant attachment security. No significant moderation effects were found between maternal EC and infant attachment security. Simple slope results showed that for infants with higher maternal reappraisal or infant sadness, maternal PT could positively predict infant attachment security. These findings highlight the importance of how the individual characteristics of mothers and infants may interact with maternal empathy during the critical period of infant attachment formation.

show abstract

“…Among many brain regions in human body, the amygdala (AMYG) is probably the key brain region to represent the discomfort perception of fabric contact pressure, because the AMYG has long been a key brain region in the production and regulation of cognitive function and emotional behavior. Abnormal changes of the AMYG not only play an important role in the pathogenesis of various diseases, but are also recognized as the root brain region of sadness, 5,6 fear, 7 anxiety, 8,9 visceral pain 10 and other negative perceptions. According to the general theory, when people were in the state of "mindfulness," which is a kind of concentrated and peaceful mind, bilateral AMYG activity would be reduced.…”

mentioning

confidence: 99%

Brain signal changes of the amygdala cortex according to the physical performance of fabric

Yuan

Wang

Shang

et al. 2022

Textile Research Journal

View full text Add to dashboard Cite

The physical properties of fabric causing an uncomfortable tactile perception under certain clothing pressure has always been a difficult problem in the field of fabric comfort research. According to a large number of works in the literature, the amygdala was recognized as the key brain region for negative perceived emotions. In order to investigate the fabric factors causing the signal changes in the amygdala brain region, functional magnetic resonance imaging was used to monitor the amygdala brain region and its anatomical sub-brain region under the same degree of compression stimulation from several different corsets, and the percent signal changes (PSCs) were extracted and analyzed. The results showed that there was a significant positive correlation between the PSCs of the centromedial group of the amygdala and the average dynamic friction coefficient (MIU) of the fabric at the level of 0.05, and a general linear model was established ( R2 = 0.998, p = 0.019). These results indicated that the surface friction properties of the fabric successfully attracted the attention of the central amygdala, and the attention increased linearly with the increase of MIU. This finding not only laid a foundation for exploring the brain perception mechanism of fabric discomfort, but also provides a possibility for further quantification of fabric discomfort perception by using the amygdala brain region.

show abstract

Maternal Depression, Child Temperament, and Early-Life Stress Predict Never-Depressed Preadolescents’ Functional Connectivity During a Negative-Mood Induction

Cited by 6 publications

References 75 publications

Structural and Functional Brain Alterations in Populations with Familial Risk for Depression: A Narrative Review

Structural and Functional Brain Alterations in Populations with Familial Risk for Depression: A Narrative Review

The effect of maternal empathy on infants’ attachment security: Moderation by maternal emotion regulation and infant temperament

Brain signal changes of the amygdala cortex according to the physical performance of fabric

Contact Info

Product

Resources

About