Maternal hepatitis B virus or hepatitis C virus carrier status as an independent risk factor for adverse perinatal outcome

Safir, Ari; Levy, Amalia; Sikuler, Emanuel; Sheiner, Eyal

doi:10.1111/j.1478-3231.2010.02218.x

Cited by 119 publications

(131 citation statements)

References 14 publications

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“…Likewise, our study, the only one performed in Europe in the last 20 years, shows no significantly increased prevalence of maternal and neonatal morbidity. In contrast, a very recent study from Israel showed significantly higher rates of perinatal mortality and low birth weight in newborns from HBsAg and/or anti-HCV-seropositive women [18]. In the Hong Kong study by To et al [17] with the still largest cohort studied with 1,340 HBsAg-positive women, there was even a lower risk for gestational hypertension and preeclampsia, but a higher prevalence of meconium-stained amniotic fluid which tended to be the case in our data as well.…”

Section: Discussionmentioning

confidence: 99%

Prevalence of Hepatitis B among Pregnant Women and Its Impact on Pregnancy and Newborn Complications at a Tertiary Hospital in the Eastern Part of Germany

Lobstein

Faber²,

Tillmann³

2010

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Background and Aims: Prevalence data of hepatitis B virus (HBV) in pregnant women in the Eastern part of Germany are missing. More importantly, no data on HBV’s impact on pregnancy is known in patients living in the Western hemisphere. Our aim was to assess the prevalence of hepatitis B surface antigen (HBsAg) and its impact on pregnancy in women admitted to the department of gynecology at a German university hospital. Patients and Methods: 8,193 women who delivered at the university hospital between 2001 and 2006 were retrospectively screened for HBsAg and if positive investigated for pregnancy and newborn complications in comparison to women without hepatitis B infection. Results:39 (0.48%) women were found to be HBsAg carriers, which is in line with other data showing lower rates in Eastern parts of Germany in relation to the Western part. Furthermore, prevalence was much lower in German-born women (0.2%) in comparison to Asian-born women (9.1%). Secondly, women with HBsAg had no significantly increased prevalence of adverse pregnancy outcomes. Conclusion: There is a low prevalence of HBV infection, especially among German-born women. There is no significant evidence to support increased complications in relation to HBV infection in our study.

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Section: Discussionmentioning

confidence: 99%

Prevalence of Hepatitis B among Pregnant Women and Its Impact on Pregnancy and Newborn Complications at a Tertiary Hospital in the Eastern Part of Germany

Lobstein

Faber²,

Tillmann³

2010

Digestion

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“…These were in concordance with studies published among other populations till date. [15][16][17] An exception is the prevalence of gestational diabetes mellitus among hepatitis carriers, which was found to be higher only in women who had an excessive weight gain during their pregnancy. The differences in BMI values may explain the diversity of the results.…”

Section: Discussionmentioning

confidence: 99%

Pattern of hepatitis B and C infection among gravid women and their newborns in a tertiary care infirmary in India

Marwah

Mohindra

Sharma

et al. 2016

Int J Reprod Contracept Obstet Gynecol

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“…47,48 HBV infection does not directly threaten maternal or fetal lives; [49][50][51][52][53][54][55] however, gestational diabetes mellitus, antepartum hemorrhage, and preterm labor have been reported in chronic carriers. [56][57][58] The most significant risk of HBV infection during pregnancy is the potential for viral transmission to the fetus or neonate, 7,[59][60][61][62] which is associated with 4.5 million cases annually. 63 More than 90% of neonates with chronic infections received hepatitis B virus from their mothers.…”

Section: 21mentioning

confidence: 99%

Viral hepatitis vaccination during pregnancy

Zhao

Jin

Zhang

et al. 2016

Human Vaccines & Immunotherapeutics

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Viral hepatitis is a serious global public health problem. It is also a common cause of jaundice and gestational complications in pregnant women. Moreover, infected mothers can transmit the virus to their fetus or neonate, which may increase disease burden and decrease quality of life. To date, commercial vaccines have been developed for hepatitis A, B, and E and are available to the general population. The Advisory Committee on Immunization Practices currently accepts emergency vaccination against hepatitis A and B during pregnancy due to benefits that overweight the potential risks. While there are limited data from trials with limited numbers of samples that suggest the efficacy or safety of hepatitis B and E vaccines in pregnant women, additional data are necessary to provide evidence of vaccination during pregnancy.

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Maternal hepatitis B virus or hepatitis C virus carrier status as an independent risk factor for adverse perinatal outcome

Abstract: Keywords congenital malformations -hepatitis Bhepatitis C -perinatal mortality -pregnancy outcome -premature rupture of membranes -preterm delivery Correspondence

Cited by 119 publications

References 14 publications

Prevalence of Hepatitis B among Pregnant Women and Its Impact on Pregnancy and Newborn Complications at a Tertiary Hospital in the Eastern Part of Germany

Prevalence of Hepatitis B among Pregnant Women and Its Impact on Pregnancy and Newborn Complications at a Tertiary Hospital in the Eastern Part of Germany

Pattern of hepatitis B and C infection among gravid women and their newborns in a tertiary care infirmary in India

Viral hepatitis vaccination during pregnancy

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