Maternally and naturally acquired antibodies to Mannheimia haemolytica and Pasteurella multocida in beef calves

Maternally and Naturally Acquired Antibody to <i>Mannheimia haemolytica</i> in Japanese Black Calves

“…Therefore, the ideal time for vaccination to calves is the period when calves have less influence of maternal antibodies, as well as they have sufficient ability to produce antibodies by themselves. Previous studies with Holstein and Hereford calves without vaccination against M. haemolytica showed that maternally acquired antibody titer against M. haemolytica decreased by 5 weeks and 60 day of age, respectively, followed by an initiation of autogenous antibody production [5, 14]. In the present study, the antibody titer against M. haemolytica decreased by 8 weeks of age in both groups.…”

“…However, little is known about passive transfer of antibody to M. haemolytica in Japanese Black calves. Previous reports demonstrated that Holstein and Hereford calves in the U.S.A. produced anti- M. haemolytica antibody following natural exposures to M. haemolytica [5, 14]. They further suggested that due to natural production of antibody, vaccinations against M. haemolytica actually induce an anamnestic rather than a primary antibody response.…”

Immunization and chemical conjugation of Bm95 obtained from Pichia pastoris enhances the immune response against vaccinal protein and Neisseria meningitidis capsular polysaccharide

“…This response is mediated by type 1 and type 2 helper T cells lymphocytes and complements the protection against a number of pathogens affecting the upper and lower respiratory tracts of humans and animals. [50][51][52][53][54] Further, immunization via the mucosal surface is an effective approach for avoiding maternal antibody interference 53,55 and is a less stressful immunization procedure.…”

Manejo do complexo respiratório bovino em confinamento: Revisão

“…Essa alta taxa de isolamento permite afirmar que a bactéria é comensal do trato respiratório superior dos bovinos, e para correlacionar esta bactéria como o agente causal do CRB, é necessário mais que o dobro do isolamento em comparado com animais sem sinais clínicos Forsberg, 2007, Dabo et al, 2007). Prado et al (2006) defendem que a P. multocida é considerada o principal agente causal do óbito dos animais em confinamento. Possivelmente a intensificação da produção de carne levou a animais que entram em confinamentos cada vez mais jovens, e a sofrerem aos desafios estressantes mais precocemente, o que favorece a colonização pulmonar por esta bactéria, contrariando pesquisas anteriores que defendiam que sumariamente a M. haemolytica era a responsável pelos casos fatais (Snowder et al, 2006, Rice et al, 2007.…”