The use of the organic Rankine cycle (ORC), organic flash cycle (OFC) and Kalina cycle (KC) is proposed to enhance the electricity generated by a supercritical CO2 recompression Brayton (SCRB) cycle. Novel comparisons of the SCRB/ORC, SCRB/OFC and SCRB/KC integrated plants from thermodynamic, exergoeconomic and sustainability perspectives are performed to choose the most appropriate bottoming cycle for waste heat recovery for the SCRB cycle. For comprehensiveness, the performance of the SCRB/OFC and SCRB/ORC layouts are examined using ten working fluids. The influence of design parameters such as pressure ratio in the supercritical CO2 (S-CO2) cycle, pinch point temperature difference in heater and pre-cooler 1, turbine inlet temperature and pressure ratio for the ORC/OFC/Kalina cycles are examined for the main system indicators including the net output power, energy and exergy efficiencies, and unit cost of power production. The order of the exergy efficiencies for the proposed systems from highest to lowest is: SCRB/ORC, SCRB/OFC and SCRB/KC. The minimum unit cost of power production for the SCRB/ORC system is lower than that for the SCRB/KC and SCRB/OFC systems, by 1.97% and 0.75%, respectively. Additionally, the highest exergy efficiencies for the SCRB/OFC and SCRB/ORC systems are achieved when n-nonane and R134a are employed as working fluids for the OFC and ORC, respectively. According to thermodynamic optimization design, the SCRB/ORC, SCRB/OFC and SCRB/KC systems exhibit sustainability indexes of 3.55, 3.47 and 3.39, respectively.