Mathematical model of gas plasma applied to chronic wounds

Wang, J. G.; Liu, X. Y.; Liu, D. W.; Lü, Xiang; Zhang, Y. T.

doi:10.1063/1.4826955

Cited by 21 publications

(14 citation statements)

References 21 publications

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“…Atmospheric pressure plasma jets (APPJ) produced in dielectric tubes have attracted considerable attentions because of their applicability in medicine for the treatment of teeth, wounds, skin, biofilms . Recently, the applications, such as the single cancer cell treatment and endoscopic surgeries have the smaller target for APPJ.…”

Section: Introductionmentioning

confidence: 99%

The Effect of Tube Diameter on an Atmospheric‐Pressure Micro‐Plasma Jet

Lü

Liu

2015

Plasma Processes & Polymers

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The micro-plasma jet is a unique way of transporting active species of plasma to small targets for applications such as a single cancer cell treatment, and endoscopic surgeries. In this letter, the authors present numerical studies on a single cylindrical electrode micro-plasma jet. The effect of tube diameter on sustaining voltage, electron density, and the density of reactive species are investigated. The diameter of the dielectric tube was varied in the range between 0.1 and 1mm. A pulsed direct current voltage with rising phase of 50 ns was used to ignite the plasma jet. The sustaining voltage monotonically increased with the decreasing diameter of the tube. More electrons wall losses happened due to the faster drift movement to the inner wall of smaller tube diameter, therefore, the decreasing pre-avalanche electron density need increasing ignition voltage to facilitate the avalanche-streamer transition as the tube diameter decreased. The increasing ignition voltage increased the chemical reactivity of plasma jet. The peak density of O 2 Ã and O increased more than 20 times as the tube diameter decreased from 1 to 0.1 mm.

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Section: Introductionmentioning

confidence: 99%

The Effect of Tube Diameter on an Atmospheric‐Pressure Micro‐Plasma Jet

Lü

Liu

2015

Plasma Processes & Polymers

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“…[1][2][3][4][5] The strongly non-equilibrium chemistry along with their physical properties of energy transfer into sensible surfaces makes them excellently suited for treatment of, e.g., chronic wounds. [6][7][8][9] The energy dissipated within the plasma is transferred into thermal, chemical, electronic, and radiative energy, to name the most relevant examples. The gas and plasma phase chemistry of these jets has been investigated quite thoroughly, and many processes have been already understood.…”

Section: Introductionmentioning

confidence: 99%

Impact of plasma jet vacuum ultraviolet radiation on reactive oxygen species generation in bio-relevant liquids

et al. 2015

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Plasma medicine utilizes the combined interaction of plasma produced reactive components. These are reactive atoms, molecules, ions, metastable species, and radiation. Here, ultraviolet (UV, 100–400 nm) and, in particular, vacuum ultraviolet (VUV, 10–200 nm) radiation generated by an atmospheric pressure argon plasma jet were investigated regarding plasma emission, absorption in a humidified atmosphere and in solutions relevant for plasma medicine. The energy absorption was obtained for simple solutions like distilled water (dH2O) or ultrapure water and sodium chloride (NaCl) solution as well as for more complex ones, for example, Rosewell Park Memorial Institute (RPMI 1640) cell culture media. As moderate stable reactive oxygen species, hydrogen peroxide (H2O2) was studied. Highly reactive oxygen radicals, namely, superoxide anion (O2•−) and hydroxyl radicals (•OH), were investigated by the use of electron paramagnetic resonance spectroscopy. All species amounts were detected for three different treatment cases: Plasma jet generated VUV and UV radiation, plasma jet generated UV radiation without VUV part, and complete plasma jet including all reactive components additionally to VUV and UV radiation. It was found that a considerable amount of radicals are generated by the plasma generated photoemission. From the experiments, estimation on the low hazard potential of plasma generated VUV radiation is discussed.

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“…Dry etching by plasma thus became a commonplace technology in semiconductor production. The plasma medicine community is currently at a similar development stage with lessons to be learned from the semiconductor processing experience, which necessitated substantial numerical modeling assisted process analysis [54]- [56].…”

Section: B Challenges and Proposed Solutionsmentioning

confidence: 99%

Low-Temperature Plasma for Biology, Hygiene, and Medicine: Perspective and Roadmap

Laroussi

Bekeschus

Keidar

et al. 2022

IEEE Trans. Radiat. Plasma Med. Sci.

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Plasma, the fourth and most pervasive state of matter in the visible universe, is a fascinating medium that is connected to the beginning of our universe itself. Man-made plasmas are at the core of many technological advances that include the fabrication of semiconductor devices, which enabled the modern computer and communication revolutions. The introduction of low temperature, atmospheric pressure plasmas to the biomedical field has ushered a new revolution in the healthcare arena that promises to introduce plasma-based therapies to combat some thorny and long-standing medical challenges. This article presents an overview of where research is at today and discusses innovative concepts and approaches to overcome present challenges and take the field to the next level. It is written by a team of experts who took an in-depth look at the various applications of plasma in hygiene, decontamination, and medicine, made critical analysis, and proposed ideas and concepts that should help the research community focus their efforts on clear and practical steps necessary to keep the field advancing for decades to come.

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Mathematical model of gas plasma applied to chronic wounds

Cited by 21 publications

References 21 publications

The Effect of Tube Diameter on an Atmospheric‐Pressure Micro‐Plasma Jet

The Effect of Tube Diameter on an Atmospheric‐Pressure Micro‐Plasma Jet

Impact of plasma jet vacuum ultraviolet radiation on reactive oxygen species generation in bio-relevant liquids

Low-Temperature Plasma for Biology, Hygiene, and Medicine: Perspective and Roadmap

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