Mating preference and sexual reinforcement in female rats

Gilman, Dennis P.; Westbrook, William H.

doi:10.1016/0031-9384(78)90195-6

Cited by 44 publications

(15 citation statements)

References 15 publications

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“…Numerous studies have shown that male rats spend more time near sexually receptive females compared to nonreceptive females [52,53]. Likewise, sexually receptive females spend more time near gonadally intact, sexually active males vs. castrated, sexually inactive males [54]. Male rats also show unconditioned preferences for the odors of sexually receptive females vs. nonreceptive females [55–57].…”

Section: Sexual Preference Paradigmsmentioning

confidence: 99%

Experimental Models for the Study of Female and Male Sexual Function

Giuliano

Pfaus

Srilatha

et al. 2010

The Journal of Sexual Medicine

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Introduction Significant progress has been made in the understanding of physiological and pharmacological mechanisms of human sexual functioning through preclinical research in animal models. Aim To provide an evidence-based documentation of the experimental models evaluating male and female sexual function for useful clinical translation. Methods Consensus discussion over the past 18 months leading to summarized views of seven experts from six countries. Main Outcome Measure Report was based on the critical analysis of scientific information available in literature and subcommittee presentations, discussions, and exchanges of ideas and feedback. Results Fundamental research in animal models has led to considerable understanding of the physiological mechanisms underlying desire, arousal, genital, and other sexual responses and the design of rational pharmacological treatments for certain sexual dysfunctions in the male and female. Tissue and cellular in vitro systems have provided critical information on the in vivo interactions and modulations in the presence and absence of chemical, biological, vascular, neurologic, endocrine, and genetic inputs. The animal models seem indispensable for elucidating the biophysiological and etiopathological aspects of male and female sexual disorders. Conclusions Useful insights into the human experience have been derived from basic research in ways that are far more difficult to obtain in humans, both scientifically and ethically. The animal model with a good predictive value can be used as a successful preclinical tool so long as the functional end points are homologous or analogous. The key issue is whether further evaluations are warranted to extrapolate the results in a clinical setting.

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Section: Sexual Preference Paradigmsmentioning

confidence: 99%

Experimental Models for the Study of Female and Male Sexual Function

Giuliano

Pfaus

Srilatha

et al. 2010

The Journal of Sexual Medicine

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“…Both external and internal variables must be considered. For example, ambient temperature determines whether pigs prefer straw bedding over bare concrete for lying (Q4, Fraser, 1985), while female rats prefer access to a male over another female only when in oestrus (Gilman and Westbrook, 1978). Second, preference depends on experience.…”

Section: Choice Testsmentioning

confidence: 99%

Using preference, motivation and aversion tests to ask scientific questions about animals’ feelings

Kirkden

Pajor

2006

Applied Animal Behaviour Science

250

179

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The past 30 years has seen an increased willingness for scientists to assess the subjective experiences of animals. There are good reasons to believe that domesticated animals are sentient beings, capable of having feelings. The study of feelings is central to the assessment of animal welfare. Feelings are not directly observable, but have measurable correlates or consequences. They can be assessed either by giving animals some control over their environments and observing the choices and decisions they make, using preference and motivation tests (including aversion tests), or by looking for signs of deprivation, frustration or distress when the animal is confined in an environment or subjected to a treatment without any means of control. Preference and motivation tests assess motivation, defined operationally as the tendency for an animal to perform a behaviour, but understood as reflecting the animal's desire to do so. These tests are used to address four distinct research questions: (1) whether an animal is motivated to obtain or avoid a resource; (2) whether it has a preference amongst alternative resources (i.e., whether it is more motivated for one than the other); (3) how strong its motivation or preference is and (4) whether its preference, or the strength of its motivation or preference, is altered by changes in its internal or external environment. Methods that have been used to answer these questions fall into two overlapping categories: choice tests and operant tests. A wide array of such tests has been employed, each with its own strengths and weaknesses. We describe individual methods, indicating the research questions they have been designed to address, list their limitations and discuss methodological problems that are not yet fully resolved. Preference and motivation tests are techniques that are still under development. However, if carefully interpreted and properly integrated with other measures of welfare, they constitute a powerful tool for the assessment of welfare.

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“…FL 326 11. 3 adaptive to females and has, among other species, previously been demonstrated in laboratory rats (Carr, Loeb, & Dissinger, 1965 ;Carr et al, 1970 ;Gilman & Westbrook, 1978), hamsters (Johnston, 1979 ;Landauer , Banks, & Carter, 1977), house mice (Scott & Pfaff, 1970), and montane voles .…”

mentioning

confidence: 88%

An automated apparatus for the assessment of social preferences in rodents

Webster

Williams

Sawrey

et al. 1984

Behavior Research Methods, Instruments, & Computers

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Preference apparatuses offer a straightforward method for the assessment of social preference in a controlled manner. The present paper provides the information necessary for the construction of an automated preference apparatus for rodents and a demonstration of the operation of this apparatus. In a representative study, Peromyscus polionotus females demonstrated preference for intact over castrated males.Ideally, social behavior and social preference should be studied in natural settings. Although this approach may be utilized successfully with diurnal and highly visible species, it is often an impractical or nearly impossible approach for many species. As an alternative , investigators have often turned to the stud y of populations in outdoor

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Mating preference and sexual reinforcement in female rats

Cited by 44 publications

References 15 publications

Experimental Models for the Study of Female and Male Sexual Function

Experimental Models for the Study of Female and Male Sexual Function

Using preference, motivation and aversion tests to ask scientific questions about animals’ feelings

An automated apparatus for the assessment of social preferences in rodents

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