Matrix-induced autologous chondrocyte implantation (MACI) for chondral defects in the patellofemoral joint

Meyerkort, Daniel; Ebert, Jay R.; Ackland, Tim; Robertson, W. B.; Fallon, Michael B.; Zheng, Minghao; Wood, David

doi:10.1007/s00167-014-3046-x

Cited by 67 publications

(115 citation statements)

References 43 publications

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“…Autologous chondrocyte implantation is an established procedure for treatment of full cartilage defects in the knee joint with several satisfactory results in the literature [19][20][21][22][23]. Although little is known about cases when joint revision surgery is needed.…”

Section: Discussionmentioning

confidence: 98%

Revision surgery after third generation autologous chondrocyte implantation in the knee

Niethammer

Valentin

Ficklscherer

et al. 2015

International Orthopaedics (SICOT)

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Section: Discussionmentioning

confidence: 98%

Revision surgery after third generation autologous chondrocyte implantation in the knee

Niethammer

Valentin

Ficklscherer

et al. 2015

International Orthopaedics (SICOT)

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“…At 24 months, 46.8% of patients exhibited complete or hypertrophic tissue infill, with a total of 78.7% of patients with infill .50%. While only a few studies that investigated ACI in the patellofemoral joint undertook some form of MRI-based assessment, 19,20,33,47 to whether MACI was performed on the patella or trochlea and with or without adjunct patellofemoral realignment. It appears that the limited studies available investigating ACI/MACI in the patellofemoral joint tended to evaluate the patient cohort overall, without any statistical analysis after group stratification based on graft location.…”

Section: Discussionmentioning

confidence: 99%

Prospective Clinical and Radiologic Evaluation of Patellofemoral Matrix-Induced Autologous Chondrocyte Implantation

Ebert

Fallon²,

Smith

et al. 2015

Am J Sports Med

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“…En este estudio reportamos el comportamiento por mapeo T2 del implante de condrocitos autólogos, el cual no se había descrito en los diferentes reportes (5,6,15,16,19,23,24) y reportamos la mejoría de los valores del tiempo de relajación del agua del implante a través del tiempo hasta llegar a valores similares al tejido nativo, los cuales persisten hasta los 48 meses.…”

Section: Discussionunclassified

Una nueva técnica artroscópica de implante de condrocitos autólogos en matriz encapsulada (ICAME) en patela: evaluación clínica y por mapeo T2 a 4 años de seguimiento

Valdés¹,

Olivos-Meza²,

Córdoba³

et al. 2018

REACA

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RESUMENPropósito: evaluar los resultados clínicos y por imagen (mapeo T2) del implante artroscópico de condrocitos autólogos en matriz encapsulada (ICAME) en lesiones condrales en patela a un seguimiento de 4 años. Métodos: se incluyeron 16 pacientes de 18 a 55 años de edad (promedio 34,37 ± 2,59) con lesión(es) condral(es) focalizadas en patela. Se les realizó el ICAME mediante artroscopia y en algunos casos se adicionó alguna de las técnicas de realineación o descompresión patelofemoral. El seguimiento clínico se evaluó mediante escalas de rodilla y la calidad del tejido de reparación se cuantificó por mapeo T2 comparándose con una zona de cartílago sano adyacente. Resultados: el tiempo de relajación del tejido de reparación (ROI-6, 54,81 ± 7,07) fue significativamente mayor al del cartílago control (ROI-3, 35,44 ± 5,51) a los 3 meses de postoperados (p < 0,001). A los 18 meses dichos valores disminuyeron sin observarse diferencia significativa entre el control (34,42 ± 3,66) y la zona de reparación (38,80 ± 6,71) (p = 0,0863) manteniéndose estable hasta ABSTRACT A new arthroscopic technique of matrix-encapsulated autologous chondrocyte implantation (MEACI) in patella: clinical and T2 mapping evaluation at 4 years of follow-up Purpose: to evaluate clinical and imaging (T2 mapping) outcomes of the arthroscopic technique of matrix-encapsulated autologous chondrocytes implantation (MEACI) in chondral lesions in patella at a follow-up of 4 years. Methods: we included 16 patients aged 18 to 55 years old (average 34.37 ± 2.59) with chondral lesion(s) localized in the patella. They underwent the arthroscopic technique of MEACI and in some cases techniques of patellofemoral realignment or decompression. Clinical follow-up was assessed using knee scores and repair tissue quality was quantified by T2-Mapping and comparing to an adjacent zone of native cartilage. Results: repair tissue relaxation time (ROI-6, 54.81 ± 7.07) was significantly higher than that of the control cartilage (ROI-3, 35.44 ± 5.51) at 3 months postoperatively (p < 0.001). At 18 months, these values decreased without a significant dif- OriginalesUna nueva técnica artroscópica de implante de condrocitos autólogos en matriz encapsulada (ICAME) en patela: evaluación clínica y por mapeo T2 a 4 años de seguimiento

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Matrix-induced autologous chondrocyte implantation (MACI) for chondral defects in the patellofemoral joint

Abstract: IV.

Cited by 67 publications

References 43 publications

Revision surgery after third generation autologous chondrocyte implantation in the knee

Revision surgery after third generation autologous chondrocyte implantation in the knee

Prospective Clinical and Radiologic Evaluation of Patellofemoral Matrix-Induced Autologous Chondrocyte Implantation

Una nueva técnica artroscópica de implante de condrocitos autólogos en matriz encapsulada (ICAME) en patela: evaluación clínica y por mapeo T2 a 4 años de seguimiento

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