Matrix Metalloproteinase-1 Genotype Contributes to the Risk of Non-solid Tumor in Childhood Leukemia

Abstract

Our results indicate that the MMP1 rs1799750 1G allele is a protective biomarker for childhood ALL.

The Contribution of Matrix Metalloproteinase-8 Promoter Polymorphism to Oral Cancer Susceptibility

“…Genomic DNA from the peripheral blood leucocytes of each participant was prepared applying the QIAamp Blood Mini Kit (Blossom, Taipei, Taiwan) and stored at -80˚C until processed as per our previous standard procedure ( [31][32][33]. The sequences of primers and the restriction enzymes for MMP-8 genotyping are designed by Terry Fox Cancer Research Lab and summarized in Table II.…”

The Contribution of Matrix Metalloproteinase-1 Genotypes to Hepatocellular Carcinoma Susceptibility in Taiwan

“…The genomic DNA from the peripheral blood leucocytes of each investigated subject was prepared applying the QIAamp Blood Mini Kit (Blossom, Taipei, Taiwan) and stored at −80˚C until processed as per our recent publications (25)(26)(27)(28). The sequences of primers and the restriction enzymes for MMP1 promoter 1607 genotyping are the same as our previous publication (29)(30)(31). Briefly, the sequences for forward and reverse primer pairs were 5'-TGACTTTTAAAACATAGTCTATGT-3' and 5'-GATTG ATTTGAGATAAGTCATAGC-3', respectively.…”

Contribution of Matrix Metalloproteinase-7 Genotypes to the Risk of Non-solid Tumor, Childhood Leukemia

“…The questionnaire recorded their disease history, diet and sleeping habit, and the disease history, diet, behavioral lifestyle and socialeconomic status of the parents. An equal number of age-matched non-cancer healthy volunteers were selected for use as a control group following initial random sampling from the Health Examination Cohort established from 2005 to 2010 as previously published (23)(24)(25)(26). The registered health practitioners in the hospital provide a multidisciplinary team approach of health assessment for the volunteers.…”