Matrix solid-phase dispersion for the liquid chromatographic determination of phenolic acids in Melissa officinalis

Ziaková, Alica; Brandšteterová, Eva; Blahová, Eva

doi:10.1016/s0021-9673(02)01712-0

Cited by 64 publications

(19 citation statements)

References 10 publications

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“…For aglycones, MSPD yielded the best extraction efficiency but for glycosides Soxhlet extraction proved to be more efficient. MSPD was also used for sample preparation of Melissa officinalis prior to liquid chromatography of rosmarinic, caffeic, and protocatechuic acids present in this herb [80]. Different MSPD sorbents and various elution agents were tested and the optimal extraction conditions were determined with the aim of obtaining extraction recoveries greater than 90% for all analytes.…”

Section: Clean-up -Isolationmentioning

confidence: 99%

Extraction, separation, and detection methods for phenolic acids and flavonoids

Stalikas¹

2007

J of Separation Science

850

539

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ReviewExtraction, separation, and detection methods for phenolic acids and flavonoidsThe impetus for developing analytical methods for phenolic compounds in natural products has proved to be multifaceted. Hundreds of publications on the analysis of this category of compounds have appeared over the past two decades. Traditional and more advanced techniques have come to prominence for sample preparation, separation, detection, and identification. This review provides an updated and extensive overview of methods and their applications in natural product matrices and samples of biological origin. In addition, it critically appraises recent developments and trends, and provides selected representative bibliographic examples.

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Section: Clean-up -Isolationmentioning

confidence: 99%

Extraction, separation, and detection methods for phenolic acids and flavonoids

Stalikas¹

2007

J of Separation Science

850

539

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“…Mencherini, Picemo, Scesa, and Aquino (2007) found that the major antioxidant components in lemon balm gathered in Italy were rosmarinic acid and luteolin. Ziaková, Brand steterová, and Blahová (2003) found that lemon balm grown in Slovakia had phenolic acids including the major rosmarinic acid, and caffeic and chlorogenic acids. Dastmalchi et al (2008) indicated that phenolic acids including caffeic, p-coumaric, protocatechuic and rosmarinic acids, and flavonoids including eriodictiol, hesperidin, hesperetin, naringin and naringenin could be determined in ethanolic extract of lemon balm cultivated in Iran; the rosmarinic acid content (96.45 mg/g ethanolic extract) was much higher than others.…”

Section: Phytochemical Contentsmentioning

confidence: 99%

Antioxidant, anti-proliferative and cyclooxygenase-2 inhibitory activities of ethanolic extracts from lemon balm (Melissa officinalis L.) leaves

Lin¹,

Chen²,

Lee³

et al. 2012

LWT

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“…The presence of this compound extracted from Rosmarinus officinalis L. is well known in the genus Salvia. The distribution in the plant kingdom and the biosynthesis, biotechnological, production and derivatives of RA is the subject of recent studies (Petersen and Simmonds 2003;Lu and Foo 1999;Exarchou et al 2002;Santos-Gomes et al 2002;Ziakova et al 2003). Because of an abundance of RA in such plants, it is considered to be a promising source of natural antioxidants.…”

Section: Introductionmentioning

confidence: 99%

Determination of Rosmarinic Acid by High-Performance Liquid Chromatography and Its Application to Certain Salvia Species and Rosemary

et al. 2010

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This study describes a method development for the determination of rosmarinic acid (RA) by using a gradient high-performance liquid chromatography (HPLC) and its application to certain plant materials. The analysis was performed by utilizing a two solvents system [A: methanol/water/formic acid (10:88:2; v:v:v); B: methanol/ water/formic acid (90:8:2; v:v:v)] on a reverse-phase column. The flow rate and injection volume were 1 ml min −1 and 10 μl, respectively. Signals were detected at 280 nm. In addition, an internal standard (IS) technique was applied for the analysis of RA to increase precision, and propylparaben was employed for this purpose. The repeatability results as RSD% were 1.66, 1.17 and 1.26 for intra-day and 1.38 was for inter-day with the employment of (3.67×10 −5 M) RA. A limit of linearity (LOL) was observed in a wide (1.13×10 −5 -5.65×10 −4 M) concentration range. Linearity parameters were also examined in the range of 5.95×10 −6 -7.14×10 −5 M RA, and very good correlation was observed. The limit of detection (LOD) and limit of quantification (LOQ) (for inter-day) were 1.60× 10 −6 M (signal/noise [S/N]=3.3) and 4.80×10 −6 M (S/N= 10), respectively. The method was applied to the extracts of certain Lamiaceae plants (Salvia candidissima Vahl. subsp. candidissima, S. sclarea L., S. verticillata L. subsp. verticillata and R. officinalis L.), and reasonable results were obtained.

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Matrix solid-phase dispersion for the liquid chromatographic determination of phenolic acids in Melissa officinalis

Cited by 64 publications

References 10 publications

Extraction, separation, and detection methods for phenolic acids and flavonoids

Extraction, separation, and detection methods for phenolic acids and flavonoids

Antioxidant, anti-proliferative and cyclooxygenase-2 inhibitory activities of ethanolic extracts from lemon balm (Melissa officinalis L.) leaves

Determination of Rosmarinic Acid by High-Performance Liquid Chromatography and Its Application to Certain Salvia Species and Rosemary

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