Mature teratoma of the thymus

Murray, James L.; Amin, Faisal Mohammad; Shah, Samir K.; Cooper, Samantha

doi:10.1136/bcr-2013-010127

Cited by 3 publications

(6 citation statements)

References 8 publications

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“…Mature mediastinal teratomas can occasionally invade the surrounding structures or they can rupture into the mediastinum or pleura. Rupture of a mature teratoma into an airway can trigger expectoration of sebum or the pathognomonic expectoration of hair (trichoptysis) [4]. Bronchiectasis secondary to exocrine secretions form the tumor have been described in patients with mature teratomas containing pancreatic acinar tissue [9].…”

Section: Discussionmentioning

confidence: 99%

“…Only occasionally magnetic resonance imaging, bronchoscopy and CT-guided biopsy are necessary in the diagnostic workup of suspected mature teratomas [4]. When the teratoma ruptures into a bronchus, hair-like material may be seen during bronchoscopy [12].…”

Section: Discussionmentioning

confidence: 99%

“…Less than 3% are located in the mediastinum [4]. Most teratomas in the mediastinum are mature teratomas, and they account for approximately 10% of all mediastinal tumors [4].…”

Section: Discussionmentioning

confidence: 99%

“…Immature teratomas, which account for approximately one third of all mediastinal germ cell tumors [5], contain fetal and neuroendocrine tissue [4]. Mature teratomas, which account for approximately two thirds of all mediastinal germ cell tumors [6], contain at least two of the three germ layers found in embryonic life: ectoderm, mesoderm and endoderm [2].…”

Section: Discussionmentioning

confidence: 99%

“…Histologically, teratomas can be classified as immature and mature [4]. Immature teratomas, which account for approximately one third of all mediastinal germ cell tumors [5], contain fetal and neuroendocrine tissue [4].…”

Section: Discussionmentioning

confidence: 99%

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Large Thoracic Teratoma with Gastro-intestinal Presentation

Fa¹,

Gumani²,

Casserly³

2016

Arch Med

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

“…Less than 3% are located in the mediastinum [4]. Most teratomas in the mediastinum are mature teratomas, and they account for approximately 10% of all mediastinal tumors [4].…”

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Large Thoracic Teratoma with Gastro-intestinal Presentation

Fa¹,

Gumani²,

Casserly³

2016

Arch Med

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Teratoma as unusual cause of chest pain, hemoptysis and dyspnea in a young patient

Hammen

Yadav

2018

Respiratory Medicine Case Reports

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A 16-year-old girl presented with intermittent left chest pain and breathlessness on exertion for last 4 months with one episode of haemoptysis. There has been loss of appetite and weight loss of 4 kg over a period of 1 month. A chest radiograph revealed a large mass like opacity with pleural effusion in the left lung field. Computerized Tomography scanning (CT scanning) and Positron Emission Tomography/Computerized Tomography scanning (PET/CT scanning) demonstrated a 7 cm round, cystic lesion in the anterior mediastinum. Pleural fluid cytology did not show any malignant cell. The patient was referred to cardiothoracic department for thoracotomy and resection. Surgery was uncomplicated with rapid recovery. Histologic findings suggested mature teratoma components surrounded by oedematous pleura and pericardium with adjacent thymus and lung tissue.

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Navigating the Diagnostic and Management Challenges of an Anterior Mediastinal Tumor: A Case Report

Reddy,

Patel,

Dongare

et al. 2024

Cureus

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Mediastinal teratomas, originating from pluripotent embryonic cells, are uncommon germ cell tumors that contain tissues from all three germ layers. Despite being the most frequent germ cell tumors in the mediastinum, they remain rare overall. This case describes a 19-year-old male who presented with chest pain, shortness of breath, and difficulty in swallowing and was ultimately diagnosed with a mature cystic teratoma in the anterior mediastinum. Imaging and histopathological analysis confirmed a large cystic teratoma, which was successfully removed via median sternotomy. Although the postoperative period was complicated by air leaks, infections, and an extended hospital stay, the patient fully recovered and was symptom-free at the one-month follow-up. This case underscores the value of comprehensive diagnostic assessment and demonstrates the favorable prognosis associated with complete surgical removal of thymic teratomas.

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Mature teratoma of the thymus

Cited by 3 publications

References 8 publications

Large Thoracic Teratoma with Gastro-intestinal Presentation

Large Thoracic Teratoma with Gastro-intestinal Presentation

Teratoma as unusual cause of chest pain, hemoptysis and dyspnea in a young patient

Navigating the Diagnostic and Management Challenges of an Anterior Mediastinal Tumor: A Case Report

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