Maxillary adenomatoid odontogenic tumor associated with a premolar

Abstract

The adenomatoid odontogenic tumor (AOT) represents 3–7% of all odontogenic tumors, and over 750 cases have been reported in the literature. This lesion was formerly considered to be a variant of the ameloblastoma and was designated as adenoameloblastoma. These lesions may infrequently produce dentinoid material and rarely enamel matrix. Consequently, the WHO (2005) classification of odontogenic lesions considered this process to represent a mixed odontogenic neoplasm. We present a case of a 12-year-old female patient with an AOT of diameter 5 cm × 5 cm located in the anterolateral region of the maxilla in association with an impacted premolar tooth. The rarity of AOT, association of this lesion with regards to maxillary premolar, the exaggerated size at presentation, the eruption of the displaced canine postoperatively and uneventful healing of the bony defect without adjunctive therapy makes this case unique.

Adenomatoid odontogenic tumor: Case series of 14 with wide range of clinical presentation

“…It is important to note, however, that AOT cases have also been described in the posterior mandible and maxilla, but rarely beyond the premolars. About 53% of AOT cases occur in the anterior maxilla, while 9% occur in the maxillary premolar region ( 11 ). About 2% of AOT cases occur in the molar region ( 11 ).…”

“…About 53% of AOT cases occur in the anterior maxilla, while 9% occur in the maxillary premolar region ( 11 ). About 2% of AOT cases occur in the molar region ( 11 ). AOT is more common in females, with a female to male ratio of close to 2:1 ( 1 , 3 , 12 ).…”

“…AOT is more common in females, with a female to male ratio of close to 2:1 ( 1 , 3 , 12 ). Almost 70% of AOT cases occur in the second decade of life, with an age range of 10-19, and rarely occur in patients above the age of 30.1 Clinically, the size of the tumor is usually small around 1-3 cm in diameter; occasionally, however, sizes larger than 3 cm are described ( 1 , 11 ). In general, AOT cases are usually mildly expansile.…”

“…Occasionally, they are asymptomatic ( 2 , 4 , 12 ). Radiographically, AOT cases usually present as well-defined to corticated unilocular radiolucent lesions; ( 9 , 11 , 13 ) about 10% demonstrate some degree of calcifications ( 14 ). Histologically, AOT is made up of epithelial cells arranged in strands of spindle-shaped cells, epithelial spheres/whorls, and cuboidal epithelial cells arranged in duct-like structures with or without calcifications ( 6 , 11 , 13 ).…”

Tumor odontogênico adenomatoide: relato de um caso clínico destacando os seus principais diagnósticos diferenciais

“…1,2 A variante folicular do TOA ocorre com maior frequência na região anterior de maxila, geralmente associada a um dente canino incluso, 1,2 características similares ao caso relatado, que, no entanto, envolvia um dente pré-molar incluso. É importante ressaltar que, de acordo com Kalia et al, 10 apenas 9% dos casos de TOA costumam acometer os dentes pré-molares superiores.…”