In this paper, we consider affine Deligne-Lusztig varieties Xw(b) and their certain union X(µ, b) inside the affine flag variety of a reductive group. Several important results in the study of affine Deligne-Lusztig varieties have been established under the so-called superregularity hypothesis. Such results include a description of generic Newton points in Iwahori double cosets of loop groups, covering relation in associated Iwahori-Weyl group and dimension formula for X(µ, b). We show that one can considerably weaken the superregularity hypothesis and sometimes completely eliminate it, thus strengthening these existing results.