The environment and the economy are negatively impacted by conventional energy sources, such as coal, gasoline, and other fossil fuels. Pakistan’s reliance on these resources has resulted in a catastrophic energy crisis. This has driven the government to make critical decisions such as early retail closures, power outages for the industrial sector, and an increase to two days a week vacations. Wind energy, accessible and affordable, will become a viable option for meeting Pakistan’s present and future energy demands. Approximately 3% of Pakistan’s land can produce nearly 132 GW of power with an installed capacity of 5 MW per km2. In this study, four zones (Karachi, Thatta, Badin, and Jamshoro) in Sindh province are assessed for the feasibility of wind energy generation. The installed capacity, generator types, and detailed specifications are provided for each zone. Moreover, the wind mapping of Pakistan is presented considering the four potential zones. The zones are analyzed using annual wind speed and power output considering wind data measured at 50 m height over one year. The higher mean speed is recorded at Jamshoro compared to other zones. The analysis indicates that all four sites are suitable for large-scale wind power generation due to their energy potential.